[HTML][HTML] Life in the cold: links between mammalian hibernation and longevity

CW Wu, KB Storey - Biomolecular Concepts, 2016 - degruyter.com
The biological process of aging is the primary determinant of lifespan, but the factors that
influence the rate of aging are not yet clearly understood and remain a challenging question …

Suspended in time: molecular responses to hibernation also promote longevity

R Al-Attar, KB Storey - Experimental Gerontology, 2020 - Elsevier
Aging in most animals is an inevitable process that causes or is a result of physiological,
biochemical, and molecular changes in the body, and has a strong influence on an …

Molecular interactions underpinning the phenotype of hibernation in mammals

MT Andrews - Journal of Experimental Biology, 2019 - journals.biologists.com
Mammals maintain a constant warm body temperature, facilitating a wide variety of
metabolic reactions. Mammals that hibernate have the ability to slow their metabolism, which …

Changes to metabolism and cell physiology that enable mammalian hibernation

BJ Klug, RM Brigham - Springer Science Reviews, 2015 - Springer
Heterothermy is a widespread, adaptive strategy used by many species of bird and mammal
to conserve energy during periods of energetic deficit, the expression of which varies greatly …

[HTML][HTML] The hibernation continuum: physiological and molecular aspects of metabolic plasticity in mammals

F van Breukelen, SL Martin - Physiology, 2015 - journals.physiology.org
Mammals are often considered to be masters of homeostasis, with the ability to maintain a
constant internal milieu, despite marked changes in the environment; however, many …

Mammalian hibernation: cellular and molecular responses to depressed metabolism and low temperature

HV Carey, MT Andrews, SL Martin - Physiological reviews, 2003 - journals.physiology.org
Carey, Hannah V., Matthew T. Andrews, and Sandra L. Martin. Mammalian Hibernation:
Cellular and Molecular Responses to Depressed Metabolism and Low Temperature. Physiol …

Out cold: biochemical regulation of mammalian hibernation–a mini-review

KB Storey - Gerontology, 2010 - karger.com
Hibernating mammals offer an intriguing example of natural torpor and illustrate the
regulatory mechanisms that control metabolic rate depression and the cell preservation …

Advances in molecular biology of hibernation in mammals

MT Andrews - Bioessays, 2007 - Wiley Online Library
Mammalian hibernation is characterized by profound reductions in metabolism, oxygen
consumption and heart rate. As a result, the animal enters a state of suspended animation …

Cellular, molecular, and physiological adaptations of hibernation: the solution to environmental challenges

SM Mohr, SN Bagriantsev… - Annual review of cell and …, 2020 - annualreviews.org
Thriving in times of resource scarcity requires an incredible flexibility of behavioral,
physiological, cellular, and molecular functions that must change within a relatively short …

Invited review: molecular adaptations in mammalian hibernators: unique adaptations or generalized responses?

F Van Breukelen, SL Martin - Journal of Applied Physiology, 2002 - journals.physiology.org
Hibernators are unique among mammals in their ability to attain, withstand, and reverse low
body temperatures. Hibernators repeatedly cycle between body temperatures near zero …