Background: Histologic and immunohistologic features of nasal polyps (NP) are similar to
those observed in asthma, thus suggesting a similar immunopathology. Objective: The …

Background There is little evidence on the efficacy of glucocorticoid transnasal nebulization
therapy in patients with eosinophilic chronic rhinosinusitis with nasal polyps (CRSwNP) …

Previous investigations have suggested that nasal secretions, obtained by lavage or
scraping, and the nasal submucosa, sampled by biopsy, are two distinct compartments. We …

The nasal antiinflammatory effects produced by maintenance treatment with topical steroids
include reduced production of cytokines. The present study explored nasal mucosal effects …

Background Airway inflammation and remodelling are important pathophysiologic features
of chronic asthma. Although current steroid use demonstrates anti‐inflammatory activity …

To define the mechanisms by which inhaled glucocorticosteroid regulates allergen-induced
airway inflammation, a double-blind, placebo-controlled, cross-over study with inhaled …

Infiltration of eosinophil granulocytes and endothelial expression of vascular cell adhesion
molecule-1 (VCAM-1) and P-selectin was investigated in biopsies of polyps and inferior …

Background: Besides being highly effective in the treatment of allergic and nonallergic
rhinitis with eosinophilia, intranasal corticosteroids appear to be useful in reducing nasal …

BACKGROUND: There is little scientific evidence to support the current practice of using oral
glucocorticosteroids and antibiotics to treat patients with chronic rhinosinusitis and nasal …

Increased mucin expression is a feature of nasal polyposis. Corticosteroids reduce polyp
size and symptoms, but their effect on mucin production remains unknown. In this study, the …