Since the discovery of aquaporins, it has become clear that the various mammalian
aquaporins play critical physiological roles in water and ion balance in multiple tissues …

Abstract Aquaporin 4 (AQP4) is the major water channel expressed in the central nervous
system (CNS), and it is primarily expressed in astrocytes. It has been studied in various brain …

Aquaporin-4 (AQP4) is the predominant water channel expressed by astrocytes in the
central nervous system (CNS). AQP4 is widely expressed throughout the brain, especially at …

Summary Aquaporin 4 (AQP 4) is the main water channel in the central nervous system
(CNS) and specifically localized to astrocyte processes. Recent studies indicate that AQP 4 …

Current experimental evidence points to the conclusion that aquaporin 4 (AQP4), which is
an important water-channel membrane protein found in the brain, could play major roles in …

Aquaporins (AQPs) represent a diverse family of membrane proteins found in prokaryotes
and eukaryotes. The primary aquaporins expressed in the mammalian brain are AQP1 …

Aquaporin-4 (AQP4) is a predominant water channel protein in mammalian brains that is
distributed with the highest density in the perivascular and subpial astrocyte end-feet. AQP4 …

Aquaporin-4 (AQP4) is expressed in astrocytes throughout the central nervous system,
particularly at the blood–brain and brain–cerebrospinal fluid barriers. Phenotype analysis of …

Background The presence of water channel proteins, aquaporins (AQPs), in the brain led to
intense research in understanding the underlying roles of each of them under normal …

Water homeostasis in the brain is of central physiologic and clinical importance. Neuronal
activity and ion water homeostasis are inextricably coupled. For example, the clearance of …