Aquaporin 1–a novel player in spinal cord injury
The role of water channel aquaporin 1 (AQP‐1) in uninjured or injured spinal cords is
unknown. AQP‐1 is weakly expressed in neurons and gray matter astrocytes, and more so …
unknown. AQP‐1 is weakly expressed in neurons and gray matter astrocytes, and more so …
Aquaporin-4: A potential therapeutic target for cerebral edema
Aquaporin-4 (AQP4) is a family member of water-channel proteins and is dominantly
expressed in the foot process of glial cells surrounding capillaries. The predominant …
expressed in the foot process of glial cells surrounding capillaries. The predominant …
Effect of TPA on aquaporin 4 mRNA expression in cultured rat astrocytes
KI Nakahama, M Nagano, A Fujioka, K Shinoda… - Glia, 1999 - Wiley Online Library
Abstract Aquaporin 4 (AQP4) is a predominant water channel protein in mammalian brains,
localized in the astrocyte plasma membrane. The regulation of AQP4 is believed to be …
localized in the astrocyte plasma membrane. The regulation of AQP4 is believed to be …
Hypersensitivity of aquaporin 4-deficient mice to 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyrindine and astrocytic modulation
Aquaporin 4 (AQP4) is a predominant water channel protein in mammalian brains, which is
localized in the astrocyte plasma membrane. AQP4 has gained much attraction due to its …
localized in the astrocyte plasma membrane. AQP4 has gained much attraction due to its …
Increased cerebral vascularization and decreased water exchange across the blood-brain barrier in aquaporin-4 knockout mice
Aquaporin-4 (AQP4) plays an important role in regulating water exchange across the blood-
brain barrier (BBB) and brain-cerebrospinal fluid interface. Studies on AQP-4 knockout mice …
brain barrier (BBB) and brain-cerebrospinal fluid interface. Studies on AQP-4 knockout mice …
Astrocyte aquaporin dynamics in health and disease
M Potokar, J Jorgačevski, R Zorec - International journal of molecular …, 2016 - mdpi.com
The family of aquaporins (AQPs), membrane water channels, consists of diverse types of
proteins that are mainly permeable to water; some are also permeable to small solutes, such …
proteins that are mainly permeable to water; some are also permeable to small solutes, such …
Acute and chronic changes in aquaporin 4 expression after spinal cord injury
O Nesic, J Lee, Z Ye, GC Unabia, D Rafati… - Neuroscience, 2006 - Elsevier
The effect of spinal cord injury (SCI) on the expression levels and distribution of water
channel aquaporin 4 (AQP4) has not been studied. We have found AQP4 in gray and white …
channel aquaporin 4 (AQP4) has not been studied. We have found AQP4 in gray and white …
In vivo expression of aquaporin‐4 by reactive microglia
M Tomás‐Camardiel, JL Venero… - Journal of …, 2004 - Wiley Online Library
Abstract Aquaporin‐4 (AQP4) is the most abundant aquaporin in the brain and it is widely
accepted that this AQP is solely expressed by astrocytes and ependymal cells. AQP4 is …
accepted that this AQP is solely expressed by astrocytes and ependymal cells. AQP4 is …
Translational readthrough generates new astrocyte AQP4 isoforms that modulate supramolecular clustering, glial endfeet localization, and water transport
M De Bellis, F Pisani, MG Mola, S Rosito, L Simone… - Glia, 2017 - Wiley Online Library
Regulation of water homeostasis is a central feature of central nervous system
pathophysiology. In this context, several lines of evidence suggest a crucial role for the water …
pathophysiology. In this context, several lines of evidence suggest a crucial role for the water …
Laminar-specific and developmental expression of aquaporin-4 in the mouse hippocampus
Mice deficient in the water channel aquaporin-4 (AQP4) demonstrate increased seizure
duration in response to hippocampal stimulation as well as impaired extracellular K+ …
duration in response to hippocampal stimulation as well as impaired extracellular K+ …