Tinnitus and hyperacusis are debilitating conditions often associated with aging or exposure
to intense noise or ototoxic drugs. One of the most reliable methods of inducing tinnitus is …

Purpose Tinnitus and hyperacusis are debilitating conditions often associated with age-,
noise-, and drug-induced hearing loss. Because of their subjective nature, the neural …

Hearing loss often triggers an inescapable buzz (tinnitus) and causes everyday sounds to
become intolerably loud (hyperacusis), but exactly where and how this occurs in the brain is …

Systemic administration of salicylate at high doses can induce reversible tinnitus and
hyperacusis in humans and animals. For this reason, a number of studies have investigated …

The neuronal mechanism underlying the phantom auditory perception of tinnitus remains
elusive at present. For over 25 years, temporary tinnitus following acute salicylate …

Tinnitus and hyperacusis are common and potentially serious hearing disorders associated
with noise-, age-or drug-induced hearing loss. Accumulating evidence suggests that tinnitus …

The amygdala, important in forming and storing memories of aversive events, is believed to
play a major role in debilitating tinnitus and hyperacusis. To explore this hypothesis, we …

Neurophysiological studies of salicylate-induced tinnitus have generally been carried out
under anesthesia, a condition that abolishes the perception of tinnitus and depresses neural …

High doses of salicylate, the anti-inflammatory component of aspirin, induce transient
tinnitus and hearing loss. Systemic injection of 250 mg/kg of salicylate, a dose that reliably …

Tinnitus, also called phantom auditory perception, is a major health problem in western
countries. As such, a significant amount of effort has been devoted to understanding its …