To measure the clinical effect of adding a whole cell pertussis component to diphtherial
tetanus vaccine (DT) given as a pre-school booster, 190 children aged 4–5 years were …

Objective. To compare the immunogenicity and reactogenicity of a diphtheria and tetanus
toxoids and three-component acellular pertussis vaccine (DTaP) with a diphtheria and …

Aim: To observe reactogenicity of a three-component acellular pertussis (aP) vaccine
simultaneously given with dT-IPV vaccine at the age of 4 years. Results: Of 813 subjects …

Prior study children from a DTaP efficacy trial were recruited at ages 5 and 15 years to
randomized booster trials addressing immunogenicity and reactogenicity; 475 preschool …

Three hundred and nineteen adolescents aged 10–12 years who had been previously
vaccinated with five doses of acellular pertussis-containing vaccines received single doses …

Diphtheria-tetanus-acellular pertussis vaccines have been licensed in the United States
since 1991. Compared with the whole cell pertussis component diphtheria-tetanus-pertussis …

Given the resurgence of pertussis despite high rates of vaccination with the diphtheria-
tetanus-acellular pertussis (DTaP) vaccine, a better understanding of vaccine-induced …

A multicenter, randomized, double-blind study was undertaken in 2342 infants to evaluate
the safety and immunogenicity of 13 acellular and 2 whole cell pertussis vaccines combined …

In a randomized double-blind trial 55 children of 15–24 months and 56 children of 4–6 years
of age previously immunized with whole-cell DTP (WC-DTP) received acellular pertussis …

Objective. This case-control study investigated the protective efficacy against pertussis of
three doses of a two-component acellular pertussis vaccine (manufactured by Biken in …