Protective effect of acellular pertussis vaccines

M Blennow, S Hedenskog, M Granström - European Journal of Clinical …, 1988 - Springer
Two acellular pertussis vaccines, a mono-component toxoid of pertussis toxin and a two-
component vaccine containing both the toxoid and filamentous haemagglutinin, were used …

Acellular pertussis vaccine: immunogenicity and safety of an acellular pertussisvs. a whole cell pertussis vaccine combined with diphtheria and tetanus toxoids as a …

ME Pichichero, TJ BADGETT… - The Pediatric …, 1987 - journals.lww.com
An acellular pertussis vaccine principally containing two purified pertussis antigens,
filamentous hemagglutinin and lymphocytosis-promoting factor, combined with diphtheria …

Clinical studies on efficacy and safety of an acellular pertussis vaccine in Aichi Prefecture, Japan.

S Isomura - Developments in biological standardization, 1991 - europepmc.org
Of 342 cases with pertussis notified from 1986 through 1989 in Aichi Prefecture, Japan, 331
(96.8%) were unimmunized children. To confirm the clinical efficacy of the acellular pertussis …

Role of whole-cell pertussis vaccine in severe local reactions to the preschool (fifth) dose of diphtheria-pertussis-tetanus vaccine.

DW Scheifele, G Bjornson, SH Halperin… - CMAJ: Canadian …, 1994 - ncbi.nlm.nih.gov
OBJECTIVE: To estimate the contribution of whole-cell pertussis vaccine to severe local
reactions after the preschool (fifth) dose of adsorbed diphtheria toxoid-pertussis vaccine …

Comparison of acellular and whole-cell pertussis-component diphtheria-tetanus-pertussis vaccines in infants

DA Blumberg, CAM Mink, JD Cherry, C Johnson… - The Journal of …, 1991 - Elsevier
In a multicenter, double-blind, randomized, longitudinal study, 252 children recelved
licensed Lederie diphtheria-tetanus toxoids and pertussis vaccine adsorbed (DTP) at 2, 4 …

A randomized double-blind trial comparing a two-component acellular to a whole-cell pertussis vaccine in Senegal

F Simondon, MP Preziosi, A Yam, CT Kane… - Vaccine, 1997 - Elsevier
A randomized, double-blind trial comparing a diphtheria-tetanus-acellular pertussis vaccine
(DTaP)(pertussis toxoid and filamentous hemagglutinin) with a whole-cell vaccine (DTwP) …

Evaluation of a new highly purified pertussis vaccine in infants and children

KM Edwards, RB Bradley, MD Decker… - Journal of infectious …, 1989 - academic.oup.com
Abstract Purified acellular pertussis vaccine (12.5 µg of lymphocytosis promoting factor [LPF]
and 12.5 µg of filamentous hemagglutinin [FHA]) was compared with conventional pertussis …

Differences of IgG antibody avidity after an acellular pertussis (aP) booster in adolescents after a whole cell (wcP) or aP primary vaccination

M Prelog, G Almanzar, N Rieber, B Ottensmeier… - Vaccine, 2013 - Elsevier
Compared to whole cell pertussis (wcP) vaccines, acellular pertussis vaccines (aP) have a
better safety profile with lower reactogenicity, although their short and long-term efficacy was …

Immunity to pertussis 5 years after booster immunization during adolescence

K Edelman, Q He, J Mäkinen, A Sahlberg… - Clinical infectious …, 2007 - academic.oup.com
Background. We conducted a 5-year follow-up study on the persistence of pertussis-specific
antibody and cell-mediated immunity after booster immunization of adolescents aged 11–13 …

A randomized comparison of reactogenicity and immunogenicity of two whole-cell pertussis vaccines

MC Steinhoff, GF Reed, MD Decker, KM Edwards… - …, 1995 - publications.aap.org
Objective. To compare prospectively the reactogenicity and immunogenicity of two licensed
whole-cell pertussis vaccines. Methods. We conducted a prospective, randomized, double …