Clues to the aetiology of neural tube malformations

CO Carter - Developmental Medicine & Child Neurology, 1974 - Wiley Online Library
The aetiology of neural tube malformations may include both genetic and environmental
elements. The genetic factors considered are:(a) a preponderance of one or other sex;(b) …

Neural tube defects: heterogeneity and homogeneity

MJ Seller, DK Kalousek, JM Opitz… - American Journal of …, 1986 - Wiley Online Library
Detailed investigations were made on 150 fetuses with neural tube defects (NTD). After
eliminating those with recognised causes, the rest were found to consist of fetuses with both …

Etiologic heterogeneity of neural-tube defects

LB Holmes, SG Driscoll, L Atkins - New England Journal of …, 1976 - Mass Medical Soc
We classified 106 stillborn and live-born infants with anencephaly, meningomyelocele,
meningocele and encephalocele according to the recognized causes of these …

The changing epidemiology of neural tube defects: United States, 1968-1989

IH Yen, MJ Khoury, JD Erickson… - American Journal of …, 1992 - jamanetwork.com
• Objective.—To describe the recent trends and epidemiologic characteristics of neural tube
defects in the United States. Research Design.—Ongoing surveillance data. Setting.—Two …

Recurrence risks for neural tube defects in a genetic counseling clinic population.

MJ Seller - Journal of Medical Genetics, 1981 - jmg.bmj.com
The recurrence of neural tube defects (NTD) in the sib following the index case of all patients
who consulted the South-East Thames Regional Health Authority Genetics Centre in the …

The recurrence risk for neural tube defects in the United States: a collaborative study

S Cowchock, E Ainbender, G Prescott… - American journal of …, 1980 - Wiley Online Library
To determine the recurrence risk for patients with one prior pregnancy affected with neural
tube defects (NTD), the authors have pooled date from eight testing centers. In 831 …

Do familial neural tube defects breed true?

E Drainer, HM May, JL Tolmie - Journal of medical genetics, 1991 - jmg.bmj.com
The tendency for sibs affected by non-syndromal neural tube defect (NTD) to have the same
type of lesion was assessed retrospectively in a series of 66 affected sibships from the west …

Evidence for multi‐site closure of the neural tube in humans

MI Van Allen, DK Kalousek, GF Chernoff… - American journal of …, 1993 - Wiley Online Library
Four separate initiation sites for neural tube (NT) fusion have been demonstrated recently in
mice and other experimental animals. We evaluated the question of whether the mult‐site …

Epidemiology and genetics of neural tube defects: an application of the Utah Genealogical Data Base

LB Jorde, RM Fineman… - American Journal of …, 1983 - Wiley Online Library
The distribution and prevalence of births with neural tube defects in Utah from 1940 to 1979
are analyzed with regard to prevalence rates, secondary sex ratios, seasonality, yearly rates …

Prenatally diagnosed neural tube defects: ultrasound, chromosome, and autopsy or postnatal findings in 212 cases

D Kennedy, D Chitayat, EJT Winsor… - American journal of …, 1998 - Wiley Online Library
Abstract From January 1990 until December 1996, 212 cases of neural tube defect (NTD)
were seen through the Prenatal Diagnosis Program of the University of Toronto. Of the 212 …