Background and aims Increased adipose tissue may promote catabolic events in skeletal
muscle. The aim of this study was to test whether high-fat diet (HFD)-induced obesity would …

Prolonged high-fat diets (HFDs) can cause intramyocellular lipid (IMCL) accumulation that
may negatively affect muscle function. We investigated the duration of a HFD required to …

Obesity and ensuing disorders are increasingly prevalent in young populations. Prolonged
exposure to high-fat diets (HFD) and excessive lipid accumulation were recently suggested …

The purpose of this study was to determine whether sarcopenic obesity accelerates
impairments in muscle maintenance through the investigation of cell cycle progression and …

Obesity and inflammation are reportedly associated with the pathogenesis of sarcopenia,
which is characterized by age‐related loss of skeletal muscle mass. Intramuscular fat …

Short‐term consumption of a high‐fat diet (HFD) can result in an oxidative shift in adult
skeletal muscle. However, the impact of HFD on young, growing muscle is largely unknown …

Obesity and aging reduce skeletal muscle contractile function. However, it remains unclear
whether obesity additively promotes muscle contractile dysfunction in the setting of aging. In …

The incidence of obesity and obesity‐related conditions, such as metabolic syndrome and
insulin resistance, is on the increase. The effect of obesity on skeletal muscle function …

Aim: Both muscle mass and strength decline with ageing, but the loss of strength far
surpasses what is projected based on the decline in mass. Interestingly, the accumulation of …

Ageing and obesity independently have been shown to significantly impair isolated muscle
contractile properties, though their synergistic effects are poorly understood. We uniquely …