Dementia is a major social and economic problem for our aging population. One of the most
common of dementia in the elderly is cerebral small vessel disease (SVD). Magnetic …

The blood vessels of the brain are lined with endothelial cells and it has been long known
that these help to regulate blood flow to the brain. However, there is increasing evidence …

Cerebral small vessel disease (SVD) is highly prevalent and a common cause of ischemic
and hemorrhagic stroke and dementia, yet the pathophysiology is poorly understood. Its …

Cerebral small vessel disease (CSVD) poses a serious socio-economic burden due to its
high prevalence and severe impact on the quality of life of elderly patients. Pathological …

The arteriosclerosis-dependent alteration of brain perfusion is one of the major determinants
in small vessel disease, since small vessels have a pivotal role in the brain's autoregulation …

Age-related cerebral small-vessel disease (CSVD) is a major cause of stroke and dementia.
Despite a widespread acceptance of small-vessel arteriopathy, lacunar infarction, diffuse …

Cerebral small vessel disease (SVD) is a major cause of age-related cognitive impairment
and dementia. The pathophysiology of SVD is not well understood and is hampered by a …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disorder of the central
nervous system wherein, after an initial phase of transient neurological defects, slow …

Cerebral small vessel disease (SVD) is characterized by changes in the pial and
parenchymal microcirculations. SVD produces reductions in cerebral blood flow and …

Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …