[HTML][HTML] Role of IL-33 in inflammation and disease

AM Miller - Journal of inflammation, 2011 - Springer
Abstract Interleukin (IL)-33 is a new member of the IL-1 superfamily of cytokines that is
expressed by mainly stromal cells, such as epithelial and endothelial cells, and its …

The evolutionary role of the IL-33/ST2 system in host immune defence

S Sattler, HH Smits, D Xu, FP Huang - Archivum immunologiae et …, 2013 - Springer
Abstract Interleukin (IL)-33 is a recently identified pleiotropic cytokine, which can orchestrate
complex innate and adaptive immune responses in immunity and disease. It has been …

Crucial and diverse role of the interleukin-33/ST2 axis in infectious diseases

O Rostan, MI Arshad, C Piquet-Pellorce… - Infection and …, 2015 - Am Soc Microbiol
ABSTRACT Interleukin-33 (IL-33) has now emerged as a cytokine with diverse and
pleiotropic functions in various infectious and inflammatory diseases. IL-33 is expressed by …

IL-33/ST2 axis in inflammation and immunopathology

M Milovanovic, V Volarevic, G Radosavljevic… - Immunologic …, 2012 - Springer
Abstract Interleukin-33 (IL-33), a member of the IL-1 family of cytokines, binds to its plasma
membrane receptor, heterodimeric complex consisted of membrane-bound ST2L and IL-1R …

[HTML][HTML] Interleukin-33 contributes to both M1 and M2 chemokine marker expression in human macrophages

AD Joshi, SR Oak, AJ Hartigan, WG Finn, SL Kunkel… - BMC immunology, 2010 - Springer
Background Interleukin-33 is a member of the IL-1 cytokine family whose functions are
mediated and modulated by the ST2 receptor. IL-33-ST2 expression and interactions have …

Interleukin 33: a switch-hitting cytokine

DO Villarreal, DB Weiner - Current Opinion in Immunology, 2014 - Elsevier
Highlights•IL-33 is a proinflammtory cytokine with pleiotropic properties.•IL-33 activities far
exceed the Th2 immunity also promoting Th1 and CD8 responses.•IL-33 can drive antiviral …

[HTML][HTML] Interleukin-33 (IL-33): A critical review of its biology and the mechanisms involved in its release as a potent extracellular cytokine

C Cayrol, JP Girard - Cytokine, 2022 - Elsevier
Abstract Interleukin-33 (IL-33), a member of the IL-1 family, is an alarmin cytokine with
crucial roles in tissue homeostasis and repair, type 2 immunity, allergic and non-allergic …

Inducible IL-33 expression by mast cells is regulated by a calcium-dependent pathway

CL Hsu, PJ Bryce - The journal of immunology, 2012 - journals.aai.org
Abstract IL-33 is an IL-1 family cytokine that displays dual functions: a cytokine via its
receptor, T1/ST2, or a chromatin-binding factor within the nucleus. Functionally, it promotes …

IL-33 is a crucial amplifier of innate rather than acquired immunity

K Oboki, T Ohno, N Kajiwara, K Arae… - Proceedings of the …, 2010 - National Acad Sciences
IL-33, a member of the IL-1-related cytokines, is considered to be a proallergic cytokine that
is especially involved in Th2-type immune responses. Moreover, like IL-1α, IL-33 has been …

[HTML][HTML] Paracrine IL-33 stimulation enhances lipopolysaccharide-mediated macrophage activation

T Ohno, K Oboki, H Morita, N Kajiwara, K Arae… - PLoS …, 2011 - journals.plos.org
Background IL-33, a member of the IL-1 family of cytokines, provokes Th2-type inflammation
accompanied by accumulation of eosinophils through IL-33R, which consists of ST2 and IL …