Costunolide protects lipopolysaccharide/d-galactosamine–induced acute liver injury in mice by inhibiting NF-κB signaling pathway
Y Wang, X Zhang, L Zhao, M Shi, Z Wei, Z Yang… - Journal of Surgical …, 2017 - Elsevier
Background Costunolide, a well-known sesquiterpene lactone, has been reported to have
anti-inflammatory and anti-oxidative effects. Methods In this study, we aim to investigate the …
anti-inflammatory and anti-oxidative effects. Methods In this study, we aim to investigate the …
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice
J Mao, M Yi, R Wang, Y Huang, M Chen - Frontiers in Pharmacology, 2018 - frontiersin.org
Costunolide, a sesquiterpene isolated from Vladimiria souliei (Franch.) Ling, is known to
exhibit anti-inflammatory, anti-viral, and anti-tumor activities. However, the effects of …
exhibit anti-inflammatory, anti-viral, and anti-tumor activities. However, the effects of …
[HTML][HTML] Catalpol protects mice against Lipopolysaccharide/D-galactosamine-induced acute liver injury through inhibiting inflammatory and oxidative response
H Zhang, R Jia, F Wang, G Qiu, P Qiao, X Xu, D Wu - Oncotarget, 2018 - ncbi.nlm.nih.gov
The purpose of this study was to investigate the protective effect of catalpol on
Lipopolysaccharide (LPS)/D-galactosamine (D-gal)-induced acute liver injury in mice. The …
Lipopolysaccharide (LPS)/D-galactosamine (D-gal)-induced acute liver injury in mice. The …
[HTML][HTML] Madecassoside prevents acute liver failure in LPS/D-GalN-induced mice by inhibiting p38/NF-κB and activating Nrf2/HO-1 signaling
W Wang, L Wu, Q Li, Z Zhang, L Xu, C Lin, L Gao… - Biomedicine & …, 2018 - Elsevier
Madecassoside (MA), a triterpenoid saponin isolated from Centella asiatica, exerts various
pharmacological activities including antioxidative and anti-inflammatory effects. The aim of …
pharmacological activities including antioxidative and anti-inflammatory effects. The aim of …
Scoparone attenuates D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure through inhibition of toll-like receptor 4 signaling in mice
The purpose of this study was to investigate the protective effects and molecular
mechanisms of scoparone on d-galactosamine (d-GalN)/lipopolysaccharide (LPS)-induced …
mechanisms of scoparone on d-galactosamine (d-GalN)/lipopolysaccharide (LPS)-induced …
Costunolide attenuates LPS-induced inflammation and lung injury through inhibiting IKK/NF-κB signaling
X Zhu, B Bai, X Ge, B Zheng, Z Xiao, Y Tang… - Naunyn-Schmiedeberg's …, 2024 - Springer
Inflammation is an important pathological process of many acute and chronic diseases, such
as sepsis, arthritis, and cancer. Many factors can lead to an inflammatory state of the body …
as sepsis, arthritis, and cancer. Many factors can lead to an inflammatory state of the body …
Costunolide protects against alcohol‐induced liver injury by regulating gut microbiota, oxidative stress and attenuating inflammation in vivo and in vitro
J Mao, H Zhan, F Meng, G Wang, D Huang… - Phytotherapy …, 2022 - Wiley Online Library
Costunolide (cos) derived from the roots of Dolomiaea souliei (Franch.), which belongs to
the Dolomiaea genus in the family Compositae, exert the anti‐inebriation effect mainly by …
the Dolomiaea genus in the family Compositae, exert the anti‐inebriation effect mainly by …
Saikosaponin a ameliorates lipopolysaccharide and d‑galactosamine-induced liver injury via activating LXRα
Y Zhu, X Chen, X Rao, C Zheng, X Peng - International …, 2019 - Elsevier
Saikosaponin a (SSa), one of the major active components of Bupleurum falcatum, has
antioxidant and anti-inflammatory pharmacological properties. However, the effects of SSa …
antioxidant and anti-inflammatory pharmacological properties. However, the effects of SSa …
Costunolide improved dextran sulfate sodium-induced acute ulcerative colitis in mice through NF-κB, STAT1/3, and Akt signaling pathways
F Xie, H Zhang, C Zheng, XF Shen - International Immunopharmacology, 2020 - Elsevier
Costunolide (CTL) is the major sesquiterpene lactone from Radix Aucklandiae, which is
widely used on the treatment of gastrointestinal diseases. However, the therapeutic effect of …
widely used on the treatment of gastrointestinal diseases. However, the therapeutic effect of …
Saikosaponin‑d alleviates carbon‑tetrachloride induced acute hepatocellular injury by inhibiting oxidative stress and NLRP3 inflammasome activation in the HL‑7702 …
L Lin, R Que, Y Shen, Y Chen… - Molecular medicine …, 2018 - spandidos-publications.com
Saikosaponin‑d (SSd) the primary active component of triterpene saponin derived from
Bupleurum falcatum L., possesses anti‑inflammatory and antioxidant properties. The present …
Bupleurum falcatum L., possesses anti‑inflammatory and antioxidant properties. The present …