Effects of disease activity on lipoprotein levels in patients with early arthritis: can oxidized LDL cholesterol explain the lipid paradox theory?

AM Fernández-Ortiz, AM Ortiz, S Pérez… - Arthritis Research & …, 2020 - Springer
Background An increased risk of cardiovascular (CV) complications has been described in
patients with rheumatoid arthritis (RA). It is the result of the combined effect of classic CV risk …

POS0092 THE SHORT-AND LONG-TERM RISK OF DEVELOPING REUMATOID ARTHRITIS IN INDIVIDUALS TESTED FOR AUTOANTIBODIES

IV Vittrup, CJ de Saint-Aubain, R Westermann… - 2024 - ard.bmj.com
Background: A proportion of healthy individuals express positivity for rheumatoid arthritis
(RA)-related autoantibodies without clinically apparent RA [1],[2]. Current research indicates …

Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se: a …

TJ van Wesemael, S Ajeganova, J Humphreys… - Arthritis research & …, 2016 - Springer
Background The contribution of smoking to rheumatoid arthritis (RA) is hypothesized to be
mediated through formation of anti-citrullinated protein antibodies (ACPA). In RA, however …

Associations with smoking and shared epitope differ between IgA‐and IgG‐class antibodies to cyclic citrullinated peptides in early rheumatoid arthritis

A Svärd, T Skogh, L Alfredsson, A Ilar… - Arthritis & …, 2015 - Wiley Online Library
Objective Smoking and HLA–DRB1/shared epitope (SE) alleles are risk factors for
rheumatoid arthritis (RA) characterized by seropositivity for antibodies targeting citrullinated …

Cardiovascular risk in persons at risk of developing rheumatoid arthritis

L van Boheemen, MH van Beers-Tas, JM Kroese… - PLoS …, 2020 - journals.plos.org
Background Rheumatoid arthritis (RA) is associated with an increased cardiovascular
disease (CVD) risk which may start even before diagnosis. To explore this CVD risk prior to …

Anti-citrullinated protein antibodies contribute to platelet activation in rheumatoid arthritis

KLL Habets, LA Trouw, EWN Levarht… - Arthritis research & …, 2015 - Springer
Introduction Although the role of platelets in rheumatoid arthritis (RA) is relatively
unexplored, recent studies point towards a contribution of platelets in arthritis. We set out to …

Prioritising referrals of individuals at-risk of RA: guidance based on results of a 10-year national primary care observational study

L Garcia-Montoya, JL Nam, L Duquenne… - Arthritis Research & …, 2022 - Springer
Background Musculoskeletal (MSK) symptoms are among the commonest reasons for
primary care assessments; however, few individuals will be diagnosed with an inflammatory …

Cross-reactivity of anti-modified protein antibodies is also present in predisease and individuals without rheumatoid arthritis

S Reijm, AS Brehler, S Rantapää-Dahlqvist… - Annals of the …, 2022 - ard.bmj.com
Figure 1 (A) ACPA, anti-CarP and AAPA IgG levels, using the CCP4, CHcitP4 and
CAcetylP4 peptides as antigen, in arbitrary units per ml (aU/mL) over time of 19 patients with …

Anti-D4GDI antibodies activate platelets in vitro: a possible link with thrombocytopenia in primary antiphospholipid syndrome

C Barbati, L Stefanini, T Colasanti, E Cipriano… - Arthritis Research & …, 2019 - Springer
Background Thrombocytopenia is a manifestation associated with primary antiphospholipid
syndrome (PAPS), and many studies have stressed the leading role played by platelets in …

P037 Anti-carbamylated protein antibodies: are they useful for the diagnosis of rheumatoid arthritis?

F Ponchel, L Hunt, M Van Delft, P Emery, L Trouw - 2019 - ard.bmj.com
Career situation of first and presenting author Resident. Introduction The current EULAR-
2010 diagnostic criteria for Rheumatoid Arthritis (RA) relies heavily on the presence of auto …