Circadian dysregulation: the next frontier in obstructive sleep apnea research
DC von Allmen, LJ Francey… - … –Head and Neck …, 2018 - journals.sagepub.com
Objective To review the effects of the circadian clock on homeostasis, the functional
interaction between the circadian clock and hypoxia-inducible factors, and the role of …
interaction between the circadian clock and hypoxia-inducible factors, and the role of …
Circadian biology in obstructive sleep apnea
BSC Koritala, Z Conroy, DF Smith - Diagnostics, 2021 - mdpi.com
Obstructive sleep apnea (OSA) is a complex process that can lead to the dysregulation of
the molecular clock, as well as 24 h rhythms of sleep and wake, blood pressure, and other …
the molecular clock, as well as 24 h rhythms of sleep and wake, blood pressure, and other …
Long-term continuous positive airway pressure treatment ameliorates biological clock disruptions in obstructive sleep apnea
Abstract Background Obstructive Sleep Apnea (OSA) is a highly prevalent and
underdiagnosed sleep disorder. Recent studies suggest that OSA might disrupt the …
underdiagnosed sleep disorder. Recent studies suggest that OSA might disrupt the …
The role of circadian rhythms in Obstructive Sleep Apnea symptoms and novel targets for treatment
I Soreca - Chronobiology International, 2021 - Taylor & Francis
ABSTRACT Obstructive Sleep Apnea (OSA) is a common disorder that is associated with
disability, premature mortality and lost quality of life. Excessive daytime sleepiness and …
disability, premature mortality and lost quality of life. Excessive daytime sleepiness and …
Is obstructive sleep apnea a circadian rhythm disorder?
J Šmon, E Kočar, T Pintar… - Journal of sleep …, 2023 - Wiley Online Library
Obstructive sleep apnea is the most common sleep‐related breathing disorder worldwide
and remains underdiagnosed. Its multiple associated comorbidities contribute to a …
and remains underdiagnosed. Its multiple associated comorbidities contribute to a …
Obstructive sleep apnea in a mouse model is associated with tissue-specific transcriptomic changes in circadian rhythmicity and mean 24-hour gene expression
Intermittent hypoxia (IH) is a major clinical feature of obstructive sleep apnea (OSA). The
mechanisms that become dysregulated after periods of exposure to IH are unclear …
mechanisms that become dysregulated after periods of exposure to IH are unclear …
Circadian clock disruptions link oxidative stress and systemic inflammation to metabolic syndrome in obstructive sleep apnea patients
X Li, X Liu, Q Meng, X Wu, X Bing, N Guo… - Frontiers in …, 2022 - frontiersin.org
Objectives: Obstructive sleep apnea (OSA) is an independent risk factor for metabolic
syndrome (MetS). Recent studies have indicated that circadian clock genes were …
syndrome (MetS). Recent studies have indicated that circadian clock genes were …
Disruption of circadian rhythm genes in obstructive sleep apnea patients—possible mechanisms involved and clinical implication
A Gabryelska, S Turkiewicz, FF Karuga… - International Journal of …, 2022 - mdpi.com
Obstructive sleep apnea (OSA) is a chronic condition characterized by recurrent pauses in
breathing caused by the collapse of the upper airways, which results in intermittent hypoxia …
breathing caused by the collapse of the upper airways, which results in intermittent hypoxia …
[HTML][HTML] Cardiac rhythm disorders in obstructive sleep apnea
GR Geovanini, G Lorenzi-Filho - Journal of thoracic disease, 2018 - ncbi.nlm.nih.gov
Obstructive sleep apnea (OSA) is common among patients with cardiac rhythm disorders.
OSA may contribute to arrhythmias due to acute mechanisms, such as generation of …
OSA may contribute to arrhythmias due to acute mechanisms, such as generation of …
Changes in Expression of the CLOCK Gene in Obstructive Sleep Apnea Syndrome Patients Are Not Reverted by Continuous Positive Airway Pressure Treatment
S Moreira, R Rodrigues, AB Barros, N Pejanovic… - Frontiers in …, 2017 - frontiersin.org
Purpose Metabolic syndrome and cardiovascular disease are strongly associated with
obstructive sleep apnea syndrome (OSAS), which causes substantial changes to normal …
obstructive sleep apnea syndrome (OSAS), which causes substantial changes to normal …