Dissociable contribution of 5-HT1A and 5-HT2A receptors in the medial prefrontal cortex to different aspects of executive control such as impulsivity and compulsive …

M Carli, M Baviera, RW Invernizzi… - …, 2006 - nature.com
Abstract Serotonin (5-HT) receptors are increasingly recognized as major targets for
cognitive enhancement in schizophrenia. Several lines of evidence suggest a …

The serotonin 5-HT2A receptors antagonist M100907 prevents impairment in attentional performance by NMDA receptor blockade in the rat prefrontal cortex

C Mirjana, M Baviera, RW Invernizzi… - …, 2004 - nature.com
We investigated whether 5-HT 2A receptors contribute to the control of attentional
performance by glutamate NMDA receptor mechanisms in the medial prefrontal cortex …

5HT1A and 5HT1B receptors of medial prefrontal cortex modulate anxiogenic-like behaviors in rats

J Solati, AA Salari, A Bakhtiari - Neuroscience letters, 2011 - Elsevier
Medial prefrontal cortex (MPFC) is one of the brain regions which play an important role in
emotional behaviors. The purpose of the present study was to evaluate the role of 5HT1A …

Dorsal–striatal 5-HT2A and 5-HT2C receptors control impulsivity and perseverative responding in the 5-choice serial reaction Time Task

L Agnoli, M Carli - Psychopharmacology, 2012 - Springer
Rational Prefrontal cortex (PFC) and dorsal striatum are part of the neural circuit critical for
executive attention. The relationship between 5-HT and aspects of attention and executive …

Intra-prefrontal 8-OH-DPAT and M100907 improve visuospatial attention and decrease impulsivity on the five-choice serial reaction time task in rats

CA Winstanley, Y Chudasama, JW Dalley… - …, 2003 - Springer
Rationale The central serotonergic systems are a major target for drugs used to treat
neuropsychiatric disorders such as depression and schizophrenia in which disruption of …

Activation of pyramidal cells in rat medial prefrontal cortex projecting to ventral tegmental area by a 5-HT1A receptor agonist

L Díaz-Mataix, F Artigas, P Celada - European Neuropsychopharmacology, 2006 - Elsevier
5-HT1A receptor agonists increase the activity of dopamine (DA) neurons in the ventral
tegmental area (VTA) and DA release in medial prefrontal cortex (mPFC). The mPFC is …

The 5-HT1A receptor agonist 8-OH-DPAT reduces rats' accuracy of attentional performance and enhances impulsive responding in a five-choice serial reaction time …

M Carli, R Samanin - Psychopharmacology, 2000 - Springer
Rationale: Whilst several studies have investigated the role of serotonergic receptor
subtypes in learning and memory, relatively few studies have examined their role in …

5-HT1A Receptor Agonists Enhance Pyramidal Cell Firing in Prefrontal Cortex Through a Preferential Action on GABA Interneurons

L Lladó-Pelfort, N Santana, V Ghisi, F Artigas… - Cerebral …, 2012 - academic.oup.com
HT1A receptors (5-HT1AR) are expressed by pyramidal and γ-aminobutyric acidergic
(GABAergic) neurons in medial prefrontal cortex (mPFC). Endogenous serotonin inhibits …

Serotonin-2C and-2a receptor co-expression on cells in the rat medial prefrontal cortex

C Nocjar, KD Alex, A Sonneborn, AI Abbas, BL Roth… - Neuroscience, 2015 - Elsevier
Neural function within the medial prefrontal cortex (mPFC) regulates normal cognition,
attention and impulse control, implicating neuroregulatory abnormalities within this region in …

The effects of a 5-HT5A receptor antagonist in a ketamine-based rat model of cognitive dysfunction and the negative symptoms of schizophrenia

A Nikiforuk, M Hołuj, T Kos, P Popik - Neuropharmacology, 2016 - Elsevier
Abstract Serotonin (5-HT) receptors still represent promising targets for the development of
novel multireceptor or stand-alone antipsychotic drugs with a potential to ameliorate …