The human T-lymphotropic virus 1 (HTLV-1) is the causative agent of HTLV-1-associated
myelopathy/tropical spastic paraparesis (HAM/TSP). The present study investigated the …

The underlying mechanisms leading to the development of human T-cell lymphotropic virus
type I (HTLV-I) associated myelopathy/tropical spastic paraparesis (HAM/TSP) in HTLV-I …

Background The polymorphisms of IL28B have been described as important in the
pathogenesis of infections caused by some viruses. The aim of this research was to evaluate …

The present study investigated the association between the rs12979860 polymorphism in
the IL‐28B gene and HTLV‐1 infection as well as the development of HTLV‐1‐associated …

HTLV‐1 is the etiologic agent of ATL and HAM/TSP. The majority of HTLV‐1‐infected
individuals remain asymptomatic, indicating that the infection alone is not sufficient to cause …

Interleukin‐18 (IL‐18) and interferon‐gamma (IFN‐γ) exert important functions in both innate
and adaptive immune responses against intracellular pathogens and viruses. Previous …

Abstract Interleukin (IL)-12, IL-18, and interferon gamma (IFN-γ) can induce Th1-
inflammatory responses in favor of HTLV-1-associated myelopathy/tropical spastic …

Background/Aims: Human T-cell lymphotropic virus type 1 (HTLV-1) is a retrovirus that
causes a persistent infection, and only 0.5-5% of infected individuals will develop HTLV-1 …

Abstract Interleukin 28B (IL28B) rs12979860 polymorphisms were examined in 41
individuals with human T-lymphotrophic virus type 1 (HTLV-1). The alleles CT/TT were more …

Abstract Background HTLV-1-associated myelopathy/tropical spastic paraparesis
(HAM/TSP) is a progressive neurological and inflammatory disease, associated with HTLV-1 …