Cryo‐electron microscopy (cryo‐EM) is a structural biological method that is used to
determine the 3D structures of biomacromolecules. After years of development, cryo‐EM has …

Background Since the introduction of what became today's standard for cryo-embedding of
biological macromolecules at native conditions more than 30 years ago, techniques and …

Cryo-electron microscopy (cryo-EM) has emerged as a powerful structure determination
technique. Its most prolific branch is single particle analysis (SPA), a method being used in a …

Cryo-electron microscopy (cryo-EM) is a structural molecular and cellular biology technique
that has experienced major advances in recent years. Technological developments in image …

Single particle cryo-electron microscopy (cryo-EM) has matured into a robust method for the
determination of biological macromolecule structures in the past decade, complementing X …

For many years, structure determination of biological macromolecules by cryo-electron
microscopy (cryo-EM) was limited to large complexes or low-resolution models. With recent …

Abstract The 2017 Nobel Prize in Chemistry was awarded to Jacques Dubochet, Joachim
Frank, and Richard Henderson for “developing cryo-electron microscopy (cryo-EM) for the …

Macromolecular machines carry out many cellular functions. Cryo-electron microscopy (cryo-
EM) is emerging as a powerful method for studying the structure, assembly and dynamics of …

Drug discovery is a crucial part of human healthcare and has dramatically benefited human
lifespan and life quality in recent centuries, however, it is usually time-and effort-consuming …

All steps of cryogenic electron-microscopy (cryo-EM) workflows have rapidly evolved over
the last decade. Advances in both single-particle analysis (SPA) cryo-EM and cryo-electron …