Botulinum neurotoxins (BoNTs) are often acquired from the digestive tract and specifically
target neuromuscular junctions where they cause an inhibition of acetylcholine release. A …

Botulism, characterized by flaccid paralysis, commonly results from botulinum neurotoxin
(BoNT) absorption across the epithelial barrier from the digestive tract and then …

Botulinum neurotoxins (BoNTs) are responsible for severe flaccid paralysis (botulism), which
in most cases enter the organism via the digestive tract and then disseminate into the blood …

Food-borne botulinum neurotoxin (BoNT) in the gastrointestinal lumen must cross an
epithelial barrier to reach peripheral nerves to mediate its toxicity. The detailed mechanism …

Botulinum neurotoxins (BoNTs) are potent toxins which induce flaccid paralysis by inhibiting
the release of acetylcholine at the neuromuscular junctions. They associate with non-toxic …

The type B botulinum neurotoxin (BoNT) elicits flaccid paralysis and death in humans by
intoxicating peripheral nerves after oral absorption. Here, we examine the function of the …

Botulism is mainly acquired by the oral route, and botulinum neurotoxin (BoNT) escapes the
gastrointestinal tract by crossing the digestive epithelial barrier prior to gaining access to the …

Botulinum neurotoxins (BoNTs) are some of the most poisonous natural toxins. Botulinum
neurotoxins associate with neurotoxin‐associated proteins (NAPs) forming large complexes …

Experiments were done to help localize the minimum essential domain within the botulinum
toxin molecule that is necessary for binding and transport across human gut epithelial cells …

Abstract Botulinum toxin A (BoNT/A) is a potent neurotoxin that acts primarily by silencing
synaptic transmission by blocking neurotransmitter release. BoNT/A comprises a light chain …