Interactions of Aspergillus fumigatus with vascular endothelial cells
Y Kamai, LY Chiang, LM Lopes Bezerra… - Medical …, 2006 - academic.oup.com
Invasive aspergillosis is characterized by two different types of angioinvasion. During
pulmonary aspergillosis, hyphae are initially outside of the pulmonary vasculature and they …
pulmonary aspergillosis, hyphae are initially outside of the pulmonary vasculature and they …
Aspergillus fumigatus Stimulates Leukocyte Adhesion Molecules and Cytokine Production by Endothelial Cells In Vitro and during Invasive Pulmonary Disease
LY Chiang, DC Sheppard, FN Gravelat… - Infection and …, 2008 - Am Soc Microbiol
Invasive aspergillosis is characterized by hyphal invasion of the blood vessels, which
contributes to the pathogenesis of this disease. During this angioinvasion, Aspergillus …
contributes to the pathogenesis of this disease. During this angioinvasion, Aspergillus …
Polarized response of endothelial cells to invasion by Aspergillus fumigatus
Y Kamai, AS Lossinsky, H Liu… - Cellular …, 2009 - Wiley Online Library
Hyphal invasion of blood vessels is a prominent feature of invasive aspergillosis. During
invasive pulmonary aspergillosis, Aspergillus fumigatus hyphae invade the abluminal …
invasive pulmonary aspergillosis, Aspergillus fumigatus hyphae invade the abluminal …
Interactions of Aspergillus fumigatus with endothelial cells: internalization, injury, and stimulation of tissue factor activity
LML Bezerra, SG Filler - Blood, 2004 - ashpublications.org
Invasive aspergillosis causes significant mortality among patients with hematologic
malignancies. This infection is characterized by vascular invasion and thrombosis. To study …
malignancies. This infection is characterized by vascular invasion and thrombosis. To study …
Fungal invasion of normally non-phagocytic host cells
SG Filler, DC Sheppard - PLoS pathogens, 2006 - journals.plos.org
Many fungi that cause invasive disease invade host epithelial cells during mucosal and
respiratory infection, and subsequently invade endothelial cells during hematogenous …
respiratory infection, and subsequently invade endothelial cells during hematogenous …
Identification of genes of Aspergillus fumigatus up-regulated during growth on endothelial cells
JC Rhodes, BG Oliver, DS Askew… - Medical …, 2001 - academic.oup.com
Aspergillus fumigatus is an important opportunistic fungal pathogen that can cause acute
invasive disease in neutropenic hosts. Invasive aspergillosis is being diagnosed with …
invasive disease in neutropenic hosts. Invasive aspergillosis is being diagnosed with …
Proangiogenic growth factors potentiate in situ angiogenesis and enhance antifungal drug activity in murine invasive aspergillosis
In invasive pulmonary aspergillosis, direct invasion and occlusion of pulmonary vasculature
by Aspergillus hyphae causes tissue hypoxia, which is enhanced by secreted fungal …
by Aspergillus hyphae causes tissue hypoxia, which is enhanced by secreted fungal …
Penetration of the Human Pulmonary Epithelium by Aspergillus fumigatus Hyphae
J Fernandes, F Hamidi, R Leborgne… - The Journal of …, 2018 - academic.oup.com
Background The airway epithelium is the first barrier interacting with Aspergillus fumigatus
conidia after their inhalation, suggesting that this structure functions as point of entry of this …
conidia after their inhalation, suggesting that this structure functions as point of entry of this …
Pathogenesis of Aspergillus fumigatus and the Kinetics of Galactomannan in an In Vitro Model of Early Invasive Pulmonary Aspergillosis: Implications for Antifungal …
WW Hope, MJ Kruhlak, CA Lyman… - The Journal of …, 2007 - academic.oup.com
Background. Little is known about the pathogenesis of invasive pulmonary aspergillosis and
the relationship between the kinetics of diagnostic markers and the outcome of antifungal …
the relationship between the kinetics of diagnostic markers and the outcome of antifungal …
Aspergillus fumigatus inhibits angiogenesis through the production of gliotoxin and other secondary metabolites
In susceptible hosts, angioinvasion by Aspergillus fumigatus triggers thrombosis, hypoxia,
and proinflammatory cytokine release, all of which are stimuli for angiogenesis. We sought …
and proinflammatory cytokine release, all of which are stimuli for angiogenesis. We sought …