Advances in the study of genetic factors and clinical interventions for fertilization failure

X Zhang, C Hu, L Wu - Journal of Assisted Reproduction and Genetics, 2023 - Springer
Fertilization failure refers to the failure in the pronucleus formation, evaluating 16-18 h post
in vitro fertilization or intracytoplasmic sperm injection. It can be caused by sperm, oocytes …

[HTML][HTML] Gene mutations associated with fertilization failure after in vitro fertilization/intracytoplasmic sperm injection

Y Xue, X Cheng, Y Xiong, K Li - Frontiers in Endocrinology, 2022 - frontiersin.org
Fertilization failure during assisted reproductive technologies (ART) is often unpredictable,
as this failure is encountered only after in vitro fertilization (IVF) and intracytoplasmic sperm …

ART failure: oocyte contributions to unsuccessful fertilization

JE Swain, TB Pool - Human reproduction update, 2008 - academic.oup.com
BACKGROUND The complexity of fertilization failure during assisted reproductive
technologies (ART) is often under-appreciated, as this failure can occur at any number of …

Improving outcomes of after fertilization failure with intracytoplasmic sperm injection: the role of differentiating oocyte-related and sperm-related oocyte activation …

KX Gross, JM Hotaling - Fertility and Sterility, 2020 - fertstert.org
Improving outcomes of after fertilization failure with intracytoplasmic sperm injection: the role of
differentiating oocyte-rela Page 1 Improving outcomes of after fertilization failure with …

Genetic mechanisms of fertilization failure and early embryonic arrest: a comprehensive review

Y Wei, J Wang, R Qu, W Zhang, Y Tan… - Human …, 2024 - academic.oup.com
BACKGROUND Infertility and pregnancy loss are longstanding problems. Successful
fertilization and high-quality embryos are prerequisites for an ongoing pregnancy. Studies …

Determinants of oocyte quality: impact on in vitro fertilization failures

CMH Combelles, VY Rawe - Oogenesis, 2013 - Springer
Fertilization failures diminish the number of zygotes available for fertility treatment. When
considering the potential etiologies of fertilization failures, oocyte determinants merit careful …

Case reports to suggest an algorithm for management of total fertilisation failure prior to use of donor gametes

JDM Nicopoullos, E Whitney, V Wells, S Batha… - Journal of assisted …, 2015 - Springer
Purpose Total fertilisation failure (TFF), even with intracytoplasmic sperm injection (ICSI),
occurs in approximately 3% of cycles, can be recurrent and the exact cause is difficult to …

[PDF][PDF] Current and future therapies for abnormal early embryogenesis with assisted reproductive technology

X Wang, Z Yao, D Liu, C Yu, H Li - Biocell, 2022 - cdn.techscience.cn
Each stage of embryonic development, including normal gamete maturation, fertilization,
zygotic genome activation, and cleavage, is crucial for human reproduction. Early embryo …

Oocyte activation deficiency: a role for an oocyte contribution?

M Yeste, C Jones, SN Amdani, S Patel… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND Infertility affects between 10 and 16% of couples worldwide. Twenty to 30%
of cases of infertility are due to a male factor, 20–35% to a female factor, and 25–40% are …

[引用][C] A function test to assess the responsibility of oocyte and sperm quality in in vitro fertilization failure

M Plachot, J Mandelbaum, AM Junca, J Cohen… - Journal of assisted …, 1993 - Springer
It is obvious that both oocyte and sperm quality play a major role in the success of in vitro
fertilization (IVF). In the case of total fertilization failure (TFF), and mainly for idiopathic …