'Beauty and the beast'in infection: How immune–endocrine interactions regulate systemic metabolism in the context of infection

FM Wensveen, M Šestan… - European journal of …, 2019 - Wiley Online Library
The immune and endocrine systems ensure two vital functions in the body. The immune
system protects us from lethal pathogens, whereas the endocrine system ensures proper …

Obesity and immunocompetence

O Lamas, A Marti, JA Martinez - European journal of clinical nutrition, 2002 - nature.com
The increasing worldwide prevalence of obesity is a major health problem since excessive
body weight constitutes a risk factor in a number of chronic diseases. It has been reported …

Obesity alters immunopathology in cancers and inflammatory diseases

X Zhang, L Gao, H Meng, A Zhang, Y Liang… - Obesity …, 2023 - Wiley Online Library
Obesity is characterized by chronic low‐grade inflammation and is strongly associated with
multiple immunological diseases, including cancer and inflammatory diseases. Recent …

Selective impairment in dendritic cell function and altered antigen‐specific CD8+ T‐cell responses in diet‐induced obese mice infected with influenza virus

AG Smith, PA Sheridan, RJ Tseng, JF Sheridan… - …, 2009 - Wiley Online Library
There is a clear link between obesity and metabolic disorders; however, little is known about
the effect of obesity on immune function, particularly during an infection. We have previously …

[HTML][HTML] Infections and immunity: associations with obesity and related metabolic disorders

A Ray, MJL Bonorden, R Pandit, KJ Nkhata… - Journal of Pathology …, 2023 - ncbi.nlm.nih.gov
About one-fourth of the global population is either overweight or obese, both of which
increase the risk of insulin resistance, cardiovascular diseases, and infections. In obesity …

[HTML][HTML] Targeting T cell (oxidative) metabolism to improve immunity to viral infection in the context of obesity

E Greene, NJ MacIver - Frontiers in Immunology, 2022 - frontiersin.org
Disorders of systemic metabolism can influence immunity. Individuals with obesity are
known to have increased inflammation, increased risk to select autoimmune diseases …

[HTML][HTML] Immunological mechanisms involved in obesity and their role in metabolic syndrome

M Góralska, M Majewska-Szczepanik… - Advances in Hygiene and …, 2015 - phmd.pl
In the past 50 years, the occurrence of human obesity has risen dramatically across the
globe. The WHO reported that at least 1.9 billion (1.9× 109) adults are overweight and 600 …

Emerging mechanisms of obesity-associated immune dysfunction

SR Shaikh, MA Beck, Y Alwarawrah… - Nature Reviews …, 2024 - nature.com
Obesity is associated with a wide range of complications, including type 2 diabetes mellitus,
cardiovascular disease, hypertension and nonalcoholic fatty liver disease. Obesity also …

Dynamic interplay between metabolic syndrome and immunity

G Paragh, I Seres, M Harangi, P Fülöp - Oxidative Stress and Inflammation …, 2014 - Springer
Obesity and its co-morbidities as metabolic syndrome, type 2 diabetes mellitus and
cardiovascular diseases are major health problems worldwide. Several reports indicated …

[HTML][HTML] Microbes and obesity—interrelationship between infection, adipose tissue and the immune system

V Hegde, NV Dhurandhar - Clinical Microbiology and Infection, 2013 - Elsevier
The world is currently experiencing an obesity epidemic as declared by the World Health
Organization. The traditional view is that behaviour leading to overeating and under-activity …