System for Targeted Delivery of Therapeutic Agents

OC Farokhzad, J Cheng, RS Langer… - US Patent App. 14 …, 2015 - Google Patents
The present invention provides systems for selec tively delivering therapeutic agents to
particular organs, tis Sues, cells, and/or intracellular compartments. In certain embodiments …

Targeting molecule linked to an imaging agent

AC Hiatt, MB Hein, JH Fitchen - US Patent 7,022,309, 2006 - Google Patents
US7022309B2 - Targeting molecule linked to an imaging agent - Google Patents
US7022309B2 - Targeting molecule linked to an imaging agent - Google Patents Targeting …

Cationic amphiphile micellar complexes

J Tousignant, S Eastman, E Lee, R Scheule… - US Patent App. 10 …, 2003 - Google Patents
The effective introduction of foreign genes and other bio logically active molecules into
targeted mammalian cells is a challenge Still facing those skilled in the art. Gene therapy, for …

Targeting peptides

A Baker, S Nicklin, S White - US Patent App. 09/990,832, 2003 - Google Patents
Disclosed is an agent which promotes the Selective uptake of material by particular cell
types. In particular, disclosed are targeting peptides which promote uptake of a material by …

Method and carrier complexes for delivering molecules to cells

H Szeto, K Zhao, H Robertson, A Birk - US Patent 8,148,322, 2012 - Google Patents
The invention relates to carrier complexes and methods for delivering molecules to cells.
The carrier complexes com prises a molecule and an aromatic cationic peptide in accor …

Method and carrier complexes for delivering molecules to cells

HH Szeto, K Zhao, HD Robertson, AV Birk - US Patent 7,704,954, 2010 - Google Patents
The invention relates to carrier complexes and methods for delivering molecules to cells.
The carrier complexes com prises a molecule and an aromatic cationic peptide in accor …

Compositions and Methods for Delivery of Antitumor Agents

KD Janda, P Wirsching, DL Boger - US Patent App. 11/630,101, 2008 - Google Patents
BACKGROUND 0004 Targeted treatment of tumors has advanced consid erably in the last
two decades, primarily due to the establish ment of monoclonal antibody (mAb) technology …

Intracellular delivery of biological effectors

C Bonny - US Patent 7,034,109, 2006 - Google Patents
Techniques enabling efficient transfer of a Substance of interest from the external medium
into cells, and particularly to cellular nuclei, are of considerable interest in the field of …

Delivery peptides, their constructs with active agents and use

H Meijer, P Wehling - US Patent App. 10/579,941, 2007 - Google Patents
0001. The present invention refers to compositions, methods, and means for the enhanced
delivery or transport of drugs, biologically active agents or other compounds as cargo or …

Bioengineered vehicles for targeted nucleic acid delivery

J Huston, P Wils, Q Zhu, O Laurent… - US Patent App. 09 …, 2002 - Google Patents
There is disclosed a gene-delivery compound comprising:(A) a single-chain binding
polypeptide having at least one effector Segment which includes at least one cysteinyl resi …