Membrane-penetrating peptides to enhance transfection and compositions and methods for using same

XDM Du Jeu - US Patent 9,856,496, 2018 - Google Patents
The present invention is directed to non-naturally occurring peptides containing a
membrane-penetrating amino acid sequence and further at least one polycationic moiety or …

Targeted vaccine delivery systems

M Zauderer, E Smith - US Patent App. 09/833,203, 2003 - Google Patents
0005 2. Background Art 0006 T lymphocytes are both key effector cells and key regulatory
cells of the immune System. The ability to Stimu late or inhibit specific T cell responses is a …

Cell penetrating peptides for intracellular delivery of molecules

G Divita, S Deshayes, K Konate, MC Morris - US Patent 10,688,194, 2020 - Google Patents
US10688194B2 - Cell penetrating peptides for intracellular delivery of molecules - Google
Patents US10688194B2 - Cell penetrating peptides for intracellular delivery of molecules …

Methods and compositions for improved retroviral gene and drug delivery

L Albritton - US Patent App. 11/175,401, 2007 - Google Patents
The present invention provides recombinant viral particles for gene therapy and liposome
compositions for drug deliv ery comprising an env protein of MMTV. The invention also …

Integrin-targeting vectors having transfection activity

SL Hart - US Patent 6,458,026, 2002 - Google Patents
A complex that comprises (i) a nucleic acid,(ii) an integrin-binding component, for example,
an integrin-binding peptide,(iii) a polycationic nucleic acid-binding component, for example …

Compositions for delivery of therapeutics and other materials

EM Bolotin, GM Castillo - US Patent 8,257,682, 2012 - Google Patents
This disclosure relates to compositions for delivering agents to a subject, and in particular, to
compositions for delivery of therapeutic agents or diagnostic agents in the presence or …

System for delivering therapeutic agents into living cells and cells nuclei

D Segev - US Patent 9,156,865, 2015 - Google Patents
The present invention relates to a novel delivery system for delivering therapeutic agents
into living cells, and more par ticularly, to novel chemical moieties that are designed capable …

System for delivering therapeutic agents into living cells and cells nuclei

D Segev - US Patent 8,293,209, 2012 - Google Patents
The present invention relates to a novel delivery system for delivering therapeutic agents
into living cells, and more par ticularly, to novel chemical moieties that are designed capable …

Molecules for targeting compounds to various selected organs or tissues

JA Heemskerk, JCT Van Deutekom… - US Patent …, 2012 - Google Patents
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Use of multi-specific, non-covalent complexes for targeted delivery of therapeutics

G Griffiths, S Govindan, H Hansen - US Patent App. 10/714,391, 2004 - Google Patents
0003. The selective delivery of therapeutic agents to diseased tissue, in Vivo, remains a
major challenge in the interests of improved therapeutic outcomes. It must be appreciated …