Compositions and methods for targeted biological delivery of molecular carriers

L Houston, S Hawley - US Patent App. 10/510,170, 2005 - Google Patents
The present invention relates to compositions and methods for the delivery of biologically-
relevant moieties to subjects in need thereof. Particles comprising a physically entrapped …

Compositions for delivery of therapeutics and other materials

EM Bolotin, GM Castillo - US Patent 7,635,463, 2009 - Google Patents
This disclosure relates to compositions for delivering agents to a subject, and in particular, to
compositions for delivery of therapeutic agents or diagnostic agents in the presence or …

Stabilized therapeutic and imaging agents

M Bednarski, N DeChene, J Pease… - US Patent App. 10 …, 2002 - Google Patents
0002 This invention relates to therapeutic and imaging agents which are comprised of a
targeting entity, a thera peutic or treatment entity and a linking carrier. In preferred agents of …

Molecules for Gene Delivery and Gene Therapy, and Methods of Use Thereof

MW Grinstaff, CAH Prata - US Patent App. 12/158,842, 2009 - Google Patents
One aspect of the present invention relates to a synthetic non-viral vector composition for
gene therapy. Another aspect of the invention relates to the use of the composition for in …

Lipophilic peptides for macromolecule delivery

LC Smith, JT Sparrow, J Hauer, MP Mims - US Patent 6,344,436, 2002 - Google Patents
Peptide-macromolecule complexes for delivery of nucleic acid to a cell. The nucleic acid
carrier includes a binding complex. The binding complex contains a binding moiety Which …

Lipophilic peptides for macromolecule delivery

L Smith, J Soarrow, J Hauer, M Mims - US Patent App. 09/805,301, 2002 - Google Patents
Peptide-macromolecule complexes for delivery of nucleic acid to a cell. The nucleic acid
carrier includes a binding complex. The binding complex contains a binding moiety which …

Targeted delivery through a cationic amino acid transporter

H Van Es, MJE Havenga, SFF Verlinden - US Patent 6,498,027, 2002 - Google Patents
The invention relates to the targeted delivery of substances to cells. The invention provides a
virus-like particle or gene delivery vehicle provided with a ligand capable of binding to a …

Cell penetrating peptides for intracellular delivery

MDT Chang, SL Fang, WI Chou, SC Lin - US Patent 8,372,951, 2013 - Google Patents
(57) ABSTRACT A cell penetrating peptide which has following sequence: NYBXBXBNQX,
wherein B represents a basic amino acid, X represents an amino acid with an aromatic, a …

Anionic cell penetrating peptide and its use for intracellular delivery

HT Chen, HF Chang, YH Wang, CL Kao - US Patent 8,614,194, 2013 - Google Patents
One aspect of the disclosure is to disclose a cell penetrating peptide Which comprises an
amino acid sequence of D” and 2sns1 5. Another aspect of the disclosure is to disclose a …

Targeting constructs for delivery of payloads

K Thurecht, C Howard, S Mahler - US Patent App. 15/548,942, 2018 - Google Patents
Disclosed are targeting constructs for targeting a target site, including a molecule or complex
of interest. The targeting constructs comprise a polymer chain and a plurality of multi-specific …