Targeted vectors for cancer immunotherapy

EM Gordon, FL Hall - US Patent 7,708,986, 2010 - Google Patents
This invention provides compositions and methods for treat ing cancer. More specifically this
invention is directed to a targeted retroviral vector comprising a cytokine gene that can be …

Delivery of a therapeutic agent in a formulation for reduced toxicity

A Klyosov, D Platt - US Patent 6,914,055, 2005 - Google Patents
BACKGROUND Many therapeutic agents typified by chemotherapeutics are effective at
treating a particular condition, but may at the Same time have toxic Side effects for the …

Delivery of a therapeutic agent in a formulation for reduced toxicity

A Klyosov, D Platt - US Patent 6,982,255, 2006 - Google Patents
BACKGROUND Many therapeutic agents typified by chemotherapeutics are effective at
treating a particular condition, but may at the Same time have toxic Side effects for the …

Delivery of a therapeutic agent in a formulation for reduced toxicity

A Klyosov, D Platt - US Patent 6,645,946, 2003 - Google Patents
BACKGROUND Many therapeutic agents typified by chemotherapeutics are effective at
treating a particular condition, but may at the Same time have toxic Side effects for the …

Targetable vector particles

WF Anderson, LF Baltrucki, JM Mason - US Patent 6,503,501, 2003 - Google Patents
(*) Notice: This patent issued on a continued pros ecution application filed under 37 CFR
Goud, et al., Virology, vol. 163, pp. 251-254 (1988). 1.53 (d), and is subject to the twenty year …

Transport agents for crossing the blood-brain barrier and into brain cancer cells and methods of use thereof

CS Hong, T Yamada, AM Fialho, TKD Gupta… - US Patent …, 2013 - Google Patents
The present invention discloses methods and materials for 5,681,810 A 10/1997 Villemez et
al. delivering a cargo compound into a brain cancer cell and/or 5,972,899 A 10/1999 …

Cell Penetrating Peptide Conjugates for Delivering of Nucleic Acids into a Cell

B Alluis, JS Fruchart - US Patent App. 12/139,542, 2009 - Google Patents
0001. This application is the US National Stage filing of International Application No.
PCT/IB2006/003642, filed Dec. 15, 2006, which claims priority to EP 05292722.5, filed Dec …

Membrane translocating peptide drug delivery system

DJ O'mahony, IJ Lambkin - US Patent 7,268,214, 2007 - Google Patents
The present invention relates to a novel membrane translo cating full-length peptide
sequence, fragment, motif, deriva tive, analog or peptidomimetic thereof (MTLPs), to nucle …

Protein Delivery System

SL Jensen - US Patent App. 11/791,917, 2009 - Google Patents
0002 At present, gene therapy of genetic or acquired dis eases Such as cystic fibrosis or
cancer generally involves one of two approaches to delivery of the therapeutic sequence …

Compositions and methods for tumor-targeted delivery of effector molecules

DG Bermudes, IC King, CA Clairmont, SL Lin… - US Patent …, 2005 - Google Patents
2001-01-30 Assigned to VION PHARMACEUTICALS, INC. reassignment VION
PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …