Polymers for delivering a substance into a cell

K Rege, RS Kane, SM Cramer… - US Patent App. 13/318,384, 2012 - Google Patents
BACKGROUND 0003 Delivery vehicles are often used to delivery a sub stance into a cell.
Viruses, for example, are effective at deliv ering DNA into mammaliancells. However …

Method of conjugating therapeutic compounds to cell targeting devices via metal complexes

RJ Heetebrij, RJ Kok, EG Talman… - US Patent App. 11 …, 2011 - Google Patents
The present invention relates to a cell-targeting complex com prising a targeting moiety and
a deliverable compound, wherein said targeting moiety and said deliverable compound are …

J chain polypeptide targeting molecule linked to an imaging agent

AC Hiatt, MB Hein, JH Fitchen - US Patent 6,391,280, 2002 - Google Patents
Polypeptide targeting molecules are provided for use in delivering imaging agents to
epithelial tissue. Upon delivery, the imaging agent (s) may remain within an epithelial cell or …

Dual secured therapeutic peptide delivery system

P Xu, B Thapa, B Cheng - US Patent 8,809,277, 2014 - Google Patents
(57) ABSTRACT A delivery system is described that includes a polymer net work that can
incorporate a therapeutic peptide for targeted delivery to a cell, eg, a cancer cell. The …

Conjugates for delivery of biologically active compounds

M Wood, H Yin - US Patent App. 13/512,432, 2012 - Google Patents
(57) ABSTRACT A construct suitable for delivery of a biologically active com pound into
cells, comprising:(d) a positively charged peptide;(e) a targeting-delivery peptide; and (f) the …

Delivery vehicles and methods for using the same

R Craig - US Patent App. 09/785,802, 2002 - Google Patents
The invention provides delivery vehicles for the intracellular delivery of a therapeutic agent
to a target Site. The delivery vehicles comprise cells loaded with an agent conjugated to an …

Tumor targeted vector

SM Kingsman, CR Bebbington, FM Ellard… - US Patent …, 2005 - Google Patents
Greco O. et al. Cancer gene therapy:'delivery, delivery, delivery. Frontiers in Biosci. 2002; 7:
d1516–1524.* Riddell SR et al. T-cell mediated rejection of gene-modi fied HIV-specific …

Transport vectors

PM Fischer, N Zhelev, S Wang - US Patent 7,153,931, 2006 - Google Patents
BACKGROUND The present invention relates to novel membrane trans location peptide
carrier moieties and membrane transloca tion vectors comprising a novel peptide carrier …

Targeted vectors for cancer immunotherapy

E Gordon, F Hall - US Patent App. 09/997,525, 2002 - Google Patents
This invention provides compositions and methods for treating cancer. More specifically this
invention is directed to a targeted retroviral vector comprising a cytokine gene that can be …

Transport vectors

PM Fischer, N Zhelev - US Patent 7,101,967, 2006 - Google Patents
BACKGROUND The present invention relates to novel membrane trans location peptide
carrier moieties and membrane transloca tion vectors comprising a novel peptide carrier …