[PDF][PDF] The correlation between antinociceptive activity of narcotics and their antagonists as measured in the mouse tail-flick test and increased synthesis of brain …

AS Bloom, WL Dewey, LS Harris, KK Brosius - Journal of Pharmacology …, 1976 - Citeseer
ABSTRACT BLOOM, ALAN S., WILLIAM L. DEWEY, LOUIS S. HARRIS AND KEITH K.
BROSIUS: The correlation between antinociceptive activity of narcotics and their antigonists …

Antagonism of morphine-induced antinociception by tetrandrine is dependent on serotonergic mechanisms

YH Zhang, LH Fang - Life Sciences, 2001 - Elsevier
1Tetrandrine (TET), a non-specific calcium antagonist, inhibited morphine-induced
antinociception in the tail-flick test in mice. This study was undertaken to assess the …

Cromakalim differentially enhances antinociception induced by agonists of alpha (2) adrenoceptors, gamma-aminobutyric acid (B), mu and kappa opioid receptors.

M Ocana, M Barrios, JM Baeyens - Journal of Pharmacology and …, 1996 - ASPET
The influence of the ATP-sensitive K+ (KATP) channel opener cromakalim on the
antinociception induced by agonists of several receptors coupled to pertussis toxin-sensitive …

Participation of opioid and monoaminergic mechanisms on the antinociceptive effect induced by tricyclic antidepressants in two behavioural pain tests in mice

O Valverderk, JA Mico, R Maldonado, M Mellado… - Progress in Neuro …, 1994 - Elsevier
1. Various clinical and experimental reports Indicate that tricyclic antidepressant drugs are
specially useful in the treatment of chronic and acute pain conditions. The present work was …

Role of adrenoceptors in the potentiation of opioid antinociception by ephedrine and phenylpropanolamine in mice

YM Dambisya, K Chan, CL Wong - Psychopharmacology, 1991 - Springer
Abstract Ephedrine and phenylpropanolamine (PPA)(10 mg/kg) pretreatment
intraperitoneally (IP) potentiated the antinociceptive effects of subcutaneous (SC) morphine …

Norepinephrine and serotonin-induced antinociception are blocked by naloxone with different dosages

Y Shou-Wei, Z Zhi-Hua, W Rui, X Yi-Fang… - Brain research …, 1994 - Elsevier
The effects of intrathecally (IT) administered naloxone (Nal) on the antinociception produced
by IT norepinephrine (NE), serotonin (5-HT), or morphine (Mor) were observed and …

Mazindol and lidocaine are antinociceptives in the mouse formalin model: involvement of dopamine receptor

AL Bittencourt, RN Takahashi - European journal of pharmacology, 1997 - Elsevier
The antinociceptive potential of mazindol, an anorectic drug, and lidocaine, an amide-type
local anesthetic, were investigated in the mouse formalin test with concurrent motor function …

Effect of alpha-adrenoceptor agonists and antagonists on imipramine-induced antinociception in the rat formalin test

MR Zarrindast, M Sahebgharani - Pharmacology, 2002 - karger.com
In this study, the effect of central administration of the α-adrenoceptor agents on the
antinociception induced by imipramine in the formalin test has been investigated …

Antagonism of antinociception produced by intrathecal clonidine by ketorolac in the rat: the role of the opioid system

GA Tejwani, AK Rattan - Anesthesia & Analgesia, 2000 - journals.lww.com
The management of severe pain may require “balanced analgesia,” involving the use of
analgesics with different modes of action. Clonidine, an α 2-adrenoreceptor agonist …

Antinociceptive effect of the GABAmimetic 4, 5, 6, 7-tetrahydroisoxazolo [5, 4-c] pyridin-3-ol (THIP): chronic treatment increases alpha-2 adrenoceptors in the mouse …

LG Costa, SD Murphy - Journal of Pharmacology and Experimental …, 1984 - ASPET
It has been shown that the gamma-aminobutyric acid mimetic THIP (4, 5, 6, 7-
tetrahydroisoxazolo [5, 4-c] pyridin-3-ol) has an antinociceptive effect in the mouse …