MATERIALS AND METHODS Animals The experiments were performed using male Wistar
rats (160—180 g). The animals were housed at a room temperature of 222 C subjected to a …

The influence of midazolam and diazepam on antinociceptive effect of morphine (10 mg/kg),
metamizol (500 mg/kg) and indomethacin (10 mg/kg) was investigated in a mouse model …

The effect of (+/−)-5-methyl-10, 11-dihydro-5H-dibenzo (a, d) cyclohepten-5, 10-imine
maleate (MK-801) or 6-cyano-7-nitroquinoxaline-2, 3-dione (CNQX) injected intrathecally (it) …

Clonidine analgesia was tested on the hyperalgesia induced by intraplantar injection of
prostaglandin E 2 or carrageenin. The antinociceptive effect of clonidine was dose …

The analgesic agent tramadol has a potent antinociceptive effect in arthritic rats. In the
present study, the actions of the selective α 2-adrenoceptor antagonists yohimbine and …

In this study, the effects of adrenoceptor agonists and antagonists on antinociception
induced by imipramine in sciatic-nerve-ligated mice were investigated. The response of …

We studied the antinociceptive interaction of systemically administered medetomidine, a
selective [alpha] 2-adrenoceptor agonist, with cocaine in the tailflick and hotplate tests in …

1. In the present work the analgesic effect of benzodiazepines (BZD) and flumazenil (FLU)
using the writhing test in mice was studied. 2. Intracerebroventricular administration of BZD …

Using the mouse tail-irmersion test (48° C), the antinociceptive effects (AE) of clonidine and
of a related analogue St-91 were examined after peripheral and intracerebroventricular (icv) …

Clenbuterol, isoproterenol and salbutamol increased the latency in the licking response of
mice on the hot plate at 56.5° C. This effect was dose-related and obtained after IP …