The role of peripheral NMDA receptors in nerve growth factor-induced muscle pain

HGH Wong - 2015 - open.library.ubc.ca
Intramuscular injections of nerve growth factor (NGF) into human masseter muscle induce a
local mechanical sensitization that mimics the symptoms of myofascial pain in patients with …

NGF-induced mechanical sensitization of the masseter muscle is mediated through peripheral NMDA receptors

H Wong, I Kang, XD Dong, N Christidis, M Ernberg… - Neuroscience, 2014 - Elsevier
Intramuscular injection of nerve growth factor (NGF) in healthy humans mimics some of the
symptoms of myofascial temporomandibular disorders (M-TMD). We hypothesized that NGF …

Peripheral mechanisms of masseter muscle nociceptor sensitization by Nerve Growth Factor (NGF)

M Wang - 2009 - open.library.ubc.ca
Myofascial temporomandibular disorders (TMD) are common chronic craniofacial conditions
that are characterized by pain in the masseter muscle. It has been suggested that nerve …

Human nerve growth factor sensitizes masseter muscle nociceptors in female rats

P Svensson, MW Wang, XD Dong, U Kumar, BE Cairns - PAIN®, 2010 - Elsevier
Injection of nerve growth factor (NGF) into the masseter muscle is not painful but does
induce a localized, quick onset (∼ 1h) and long-lasting mechanical sensitization in healthy …

Peripheral mechanisms of nerve growth factor-induced masticatory muscle sensitization: a model of temporomandibular disorders pain

MK Mann - 2005 - open.library.ubc.ca
It has been speculated that Nerve Growth Factor (NGF), a neurotrophic protein, may play a
role in the pathophysiology of temporomandibular disorders (TMD). TMD are characterized …

Effects of NGF-induced muscle sensitization on proprioception and nociception

P Svensson, K Wang, L Arendt-Nielsen… - Experimental brain …, 2008 - Springer
Temporomandibular disorders (TMDs) are associated with perturbation of proprioceptive
and nociceptive function. Recent studies have shown that injection of the neurotrophic …

[PDF][PDF] Influence of intramuscular nerve growth factor injection on the response properties of rat masseter muscle afferent fibers.

MK Mann, XD Dong, P Svensson… - Journal of orofacial …, 2006 - researchgate.net
Aims: To investigate whether local administration of nerve growth factor (NGF) decreases
the mechanical threshold (MT) of putative nociceptive masseter afferent fibers as part of its …

Nerve growth factor alters the sensitivity of rat masseter muscle mechanoreceptors to NMDA receptor activation

H Wong, XD Dong, BE Cairns - Journal of Neurophysiology, 2014 - journals.physiology.org
Intramuscular injection of nerve growth factor (NGF) into rat masseter muscle induces a local
mechanical sensitization that is greater in female than in male rats. The duration of NGF …

Nerve growth factor and glutamate increase the density and expression of substance P-containing nerve fibers in healthy human masseter muscles

AM Alhilou, A Shimada, CI Svensson, P Svensson… - Scientific Reports, 2021 - nature.com
Nocifensive behavior induced by injection of glutamate or nerve growth factor (NGF) into rats
masseter muscle is mediated, in part, through the activation of peripheral NMDA receptors …

Nerve growth factor-evoked masseter muscle sensitization and perturbation of jaw motor function in healthy women.

P Svensson, E Castrillon… - Journal of orofacial …, 2008 - search.ebscohost.com
Aim: To replicate and extend previous findings of nerve growth factor (NGF)-induced
mechanical sensitization in healthy young men to women and test for associations between …