Historical review: cytokines as therapeutics and targets of therapeutics
J Vilček, M Feldmann - Trends in pharmacological sciences, 2004 - cell.com
Cytokine research has spawned the introduction of new therapies that have revolutionized
the treatment of many important diseases. These therapeutic advances have resulted from …
the treatment of many important diseases. These therapeutic advances have resulted from …
Cytokines and anti-cytokines as therapeutics—An update
V Tayal, BS Kalra - European journal of pharmacology, 2008 - Elsevier
Cytokines which comprise of a family of proteins—interleukins, lymphokines, monokines,
interferons, and chemokines, are important components of the immune system. They act in …
interferons, and chemokines, are important components of the immune system. They act in …
Clinical applications of cytokines: role in pathogenesis, diagnosis, and therapy
JJ Oppenheim, JL Rossio, AJH Gearing - 1993 - books.google.com
The driving force for research on cytokines has always been their clinical promise. Their
biological properties suggested a key role in hematopoiesis, immunity, tumor genesis …
biological properties suggested a key role in hematopoiesis, immunity, tumor genesis …
Cytokines as therapeutic drugs
H Schooltink, S Rose-John - Journal of interferon & cytokine …, 2002 - liebertpub.com
Cytokines are a growing group of proteins that are responsible for the communication of
cells of the immune system, hematopoietic cells, and other cell types. They play a dominant …
cells of the immune system, hematopoietic cells, and other cell types. They play a dominant …
Cytokine therapeutics: lessons from interferon alpha.
JU Gutterman - Proceedings of the National Academy of …, 1994 - National Acad Sciences
Cytokines are soluble proteins that allow for communication between cells and the external
environment. Interferon (IFN) alpha, the first cytokine to be produced by recombinant DNA …
environment. Interferon (IFN) alpha, the first cytokine to be produced by recombinant DNA …
Cytokines: principles and prospects
A Kelso - Immunology and cell biology, 1998 - Wiley Online Library
Cytokines participate in the induction and effector phases of all immune and inflammatory
responses. They are therefore obvious tools and targets for strategies designed to promote …
responses. They are therefore obvious tools and targets for strategies designed to promote …
[PDF][PDF] Cytokines & their physiologic and pharmacologic functions in inflammation: A review.
PZ Shaikh - International Journal of Pharmacy & Life Sciences, 2011 - academia.edu
Inflammation is mediated by a variety of soluble factors, including a group of secreted
polypeptides known as cytokines. Inflammatory cytokines can be divided into two groups …
polypeptides known as cytokines. Inflammatory cytokines can be divided into two groups …
Small molecules to the rescue: Inhibition of cytokine signaling in immune-mediated diseases
M Gadina, N Gazaniga, L Vian, Y Furumoto - Journal of autoimmunity, 2017 - Elsevier
Cytokines are small, secreted proteins associated with the maintenance of immune
homeostasis but also implicated with the pathogenesis of several autoimmune and …
homeostasis but also implicated with the pathogenesis of several autoimmune and …
Cytokines as therapeutic targets in rheumatoid arthritis and other inflammatory diseases
S Siebert, A Tsoukas, J Robertson, I McInnes - Pharmacological reviews, 2015 - ASPET
The human immune system involves highly complex and coordinated processes in which
small proteins named cytokines play a key role. Cytokines have been implicated in the …
small proteins named cytokines play a key role. Cytokines have been implicated in the …