The human immune system involves highly complex and coordinated processes in which
small proteins named cytokines play a key role. Cytokines have been implicated in the …

Cytokines as Therapeutic Targets: Advances and Limitations: Immunity Skip to Main Content
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This chapter described the physiologic, pharmacologic, and pathologic effects of cytokines.
They are glycosylated small polypeptides, synthesized and released by a variety of sources …

Cytokines are critical mediators of protective host responses, including defense against
microbial invasion and tumorigenesis. However, the production of specific proinflammatory …

Brian Henderson and Simon Blake lnrerleukin 2 is just one of a large, growing, collection of
potent cytokines that are produced by a variety of cells and have a myriad of overlapping …

There is an emerging concept that the net biological response of pro and anti-inflammatory
cytokines affects the outcome of certain diseases. In inflammatory diseases, interleukin-1 (IL …

This review provides an historical account of the discovery and development of cytokines.
Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular …

Cytokines affect nearly every biological process; these include embryonic development,
disease pathogenesis, non‐specific response to infection, specific response to antigen …

Cytokines are secreted or membrane-presented molecules that mediate broad cellular
functions, including development, differentiation, growth and survival. Accordingly, the …