Steroid 5α-reductase deficiency in a 65-year-old male pseudohermaphrodite: the natural history, ultrastructure of the testes, and evidence for inherited enzyme …
J Imperato-McGinley, RE Peterson… - The Journal of …, 1980 - academic.oup.com
We report a 65-yr-old male pseudohermaphrodite with steroid 5α-reductase deficiency in
whom there was no medical intervention before, during, or after puberty, enabling us to …
whom there was no medical intervention before, during, or after puberty, enabling us to …
Familial male pseudohermaphroditism due to deficiency of 5α‐reductase
MO Savage, MA Preece, SL Jeffcoate… - Clinical …, 1980 - Wiley Online Library
Two brothers of Greek Cypriot origin, karyotype 46 XY, aged 17 and 19 years were brought
up as females because of predominantly female external genitalia with clitoromegaly and …
up as females because of predominantly female external genitalia with clitoromegaly and …
Male pseudohermaphroditism resulting from a novel mutation in the human steroid 5 alpha-reductase type 2 gene (SRD5A2).
R Anwar, SG Gilbey, JP New, AF Markham - Molecular Pathology, 1997 - ncbi.nlm.nih.gov
The enzyme steroid 5 alpha-reductase, via NADPH, catalyses the conversion of testosterone
to dihydrotestosterone, which is required for the embryonic differentiation of the external …
to dihydrotestosterone, which is required for the embryonic differentiation of the external …
Steroid 5α-reductase 2 deficiency
JD Wilson, JE Griffin, DW Russell - Endocrine Reviews, 1993 - academic.oup.com
I. Introduction B ETWEEN 1968 and 1973 a large body of evidence accumulated in our
laboratory and by others demonstrated that the conversion of testosterone to …
laboratory and by others demonstrated that the conversion of testosterone to …
Steroid 5α-reductase 2 deficiency
Dihydrotestosterone is a potent androgen metabolite formed from testosterone by action of
5α-reductase isoenzymes. Mutations in the type 2 isoenzyme cause a disorder of 46, XY sex …
5α-reductase isoenzymes. Mutations in the type 2 isoenzyme cause a disorder of 46, XY sex …
[引用][C] Steroid 5α-reductase: two genes/two enzymes
DW Russell, JD Wilson - Annual review of biochemistry, 1994 - annualreviews.org
Virilization in mammals is mediated by two steroid hormones, testosterone and
dihydrotestosterone. Both hormones bind to a typical steroid hormone receptor, the …
dihydrotestosterone. Both hormones bind to a typical steroid hormone receptor, the …
Clinical, biochemical, and genetic findings in a large pedigree of male and female patients with 5 alpha-reductase 2 deficiency
Z Hochberg, R Chayen, N Reiss, Z Falik… - The Journal of …, 1996 - academic.oup.com
The present report describes a cluster of eight patients with male pseudohermaphroditism
from a large pedigree with steroid 5 alpha-reductase 2 deficiency (5 alpha RD), who reside …
from a large pedigree with steroid 5 alpha-reductase 2 deficiency (5 alpha RD), who reside …
Male pseudohermaphroditism due to steroid 5α-reductase deficiency
RE Peterson, J Imperato-McGinley, T Gautier… - The American journal of …, 1977 - Elsevier
A new inherited form of male pseudohermaphroditism has been investigated in a pedigree
of 24 families with 38 affected males. At birth, the affected males (46 XY) have a clitoral-like …
of 24 families with 38 affected males. At birth, the affected males (46 XY) have a clitoral-like …
Molecular genetics of steroid 5 alpha-reductase 2 deficiency.
AE Thigpen, DL Davis, A Milatovich… - The Journal of …, 1992 - Am Soc Clin Investig
Two isozymes of steroid 5 alpha-reductase encoded by separate loci catalyze the
conversion of testosterone to dihydrotestosterone. Inherited defects in the type 2 isozyme …
conversion of testosterone to dihydrotestosterone. Inherited defects in the type 2 isozyme …
URINARY STEROID METABOLITES IN SUBJECTS WITH MALE PSEUDOHERMAPHRODITISM DUE TO 5α‐REDUCTASE DEFICIENCY
RE Peterson, J IMPERATO‐McGINLEY… - Clinical …, 1985 - Wiley Online Library
To investigate the enzymatic basis for abnormal steroid metabolism in subjects with male
pseudohermaphroditism due to 5α‐reductase deficiency, the ring A reduced urinary 5β and …
pseudohermaphroditism due to 5α‐reductase deficiency, the ring A reduced urinary 5β and …
相关搜索
- male pseudohermaphrodite natural history
- male pseudohermaphrodite ultrastructure of the testes
- male pseudohermaphrodite enzyme heterogeneity
- male pseudohermaphrodite 65 year
- natural history ultrastructure of the testes
- natural history enzyme heterogeneity
- natural history 65 year
- enzyme heterogeneity ultrastructure of the testes
- 65 year ultrastructure of the testes
- 65 year enzyme heterogeneity
- human steroid male pseudohermaphroditism
- human steroid alpha reductase
- alpha reductase male pseudohermaphroditism
- steroid metabolites male pseudohermaphroditism