Unwanted antibody responses significantly impact human health, and current options for
treating deleterious antibody responses largely rely on broad immunosuppressants that can …

Current treatments for unwanted antibody responses largely rely on immunosuppressive
drugs compromising overall immunity. New approaches to achieve antigen-specific …

Targeted immune tolerance is a coveted therapy for the treatment of a variety of autoimmune
diseases, as current treatment options often involve nonspecific immunosuppression …

Autoimmune diseases are characterized by aberrant immune responses toward self-
antigens. Current treatments lack specificity, promoting adverse effects by broadly …

Antibody responses provide critical protective immunity to a wide array of pathogens. There
remains a high interest in generating robust antibodies for vaccination as well as understand …

Autoimmune diseases (AIDs) are caused by the loss of self-tolerance and destruction of
tissues by the host's immune system. Several antigen-specific immunotherapies, focused on …

Stimulation of monocytes with immunomodulating agents can harness the immune system to
treat a long range of diseases, including cancers, infections and autoimmune diseases. To …

Multiple sclerosis (MS) is an autoimmune disease where myelin is incorrectly recognized as
foreign and attacked by the adaptive immune system. Dendritic cells (DCs) direct adaptive …

Tolerogenic nanoparticles (NPs) are rapidly being developed as specific immunotherapies
to treat autoimmune disease. However, many NP-based therapies conjugate antigen (Ag) …

Liposomal vaccines incorporating adjuvant and CD4 T cell helper peptides enhance
antibody responses against weakly immunogenic B cell epitopes such as found in the …