[HTML][HTML] Developing Wolbachia-based disease interventions for an extreme environment
PA Ross, S Elfekih, S Collier, MJ Klein, SS Lee… - PLoS …, 2023 - journals.plos.org
Aedes aegypti mosquitoes carrying self-spreading, virus-blocking Wolbachia bacteria are
being deployed to suppress dengue transmission. However, there are challenges in …
being deployed to suppress dengue transmission. However, there are challenges in …
[HTML][HTML] Wolbachia Infections Are Virulent and Inhibit the Human Malaria Parasite Plasmodium Falciparum in Anopheles Gambiae
Endosymbiotic Wolbachia bacteria are potent modulators of pathogen infection and
transmission in multiple naturally and artificially infected insect species, including important …
transmission in multiple naturally and artificially infected insect species, including important …
[HTML][HTML] Aedes aegypti insecticide resistance underlies the success (and failure) of Wolbachia population replacement
GA Garcia, AA Hoffmann, R Maciel-de-Freitas… - Scientific reports, 2020 - nature.com
Mosquitoes that carry Wolbachia endosymbionts may help control the spread of arboviral
diseases, such as dengue, Zika and chikungunya. Wolbachia frequencies systematically …
diseases, such as dengue, Zika and chikungunya. Wolbachia frequencies systematically …
Using Wolbachia for dengue control: insights from modelling
Dengue is the most common arboviral infection of humans, responsible for a substantial
disease burden across the tropics. Traditional insecticide-based vector-control programmes …
disease burden across the tropics. Traditional insecticide-based vector-control programmes …
[HTML][HTML] Replacing a Native Wolbachia with a Novel Strain Results in an Increase in Endosymbiont Load and Resistance to Dengue Virus in a Mosquito Vector
Wolbachia is a maternally transmitted endosymbiotic bacterium that is estimated to infect up
to 65% of insect species. The ability of Wolbachia to both induce pathogen interference and …
to 65% of insect species. The ability of Wolbachia to both induce pathogen interference and …
Harnessing mosquito–Wolbachia symbiosis for vector and disease control
Mosquito species, members of the genera Aedes, Anopheles and Culex, are the major
vectors of human pathogens including protozoa (Plasmodium sp.), filariae and of a variety of …
vectors of human pathogens including protozoa (Plasmodium sp.), filariae and of a variety of …
Wolbachia-mediated virus blocking in the mosquito vector Aedes aegypti
G Terradas, EA McGraw - Current opinion in insect science, 2017 - Elsevier
Highlights•Wolbachia-mediated blocking is density dependent in most associations and
tends to be greater in novel infections.•Immune priming is commonly seen in novelly …
tends to be greater in novel infections.•Immune priming is commonly seen in novelly …
[HTML][HTML] Viral RNA is a target for Wolbachia-mediated pathogen blocking
The ability of the endosymbiont Wolbachia pipientis to restrict RNA viruses is presently
being leveraged to curb global transmission of arbovirus-induced diseases. Past studies …
being leveraged to curb global transmission of arbovirus-induced diseases. Past studies …
Mechanisms of horizontal cell-to-cell transfer of Wolbachia spp. in Drosophila melanogaster
Wolbachia is an intracellular endosymbiont present in most arthropod and filarial nematode
species. Transmission between hosts is primarily vertical, taking place exclusively through …
species. Transmission between hosts is primarily vertical, taking place exclusively through …
[HTML][HTML] The spread of Wolbachia through mosquito populations
FM Jiggins - PLoS biology, 2017 - journals.plos.org
In many regions of the world, mosquito-borne viruses pose a growing threat to human
health. As an alternative to traditional control measures, the bacterial symbiont Wolbachia …
health. As an alternative to traditional control measures, the bacterial symbiont Wolbachia …