[HTML][HTML] Wolbachia endosymbionts and human disease control

BE Slatko, AN Luck, SL Dobson, JM Foster - Molecular and biochemical …, 2014 - Elsevier
Most human filarial nematode parasites and arthropods are hosts for a bacterial
endosymbiont, Wolbachia. In filaria, Wolbachia are required for normal development, fertility …

Wolbachia and Virus Alter the Host Transcriptome at the Interface of Nucleotide Metabolism Pathways

ARI Lindsey, T Bhattacharya, RW Hardy, ILG Newton - MBio, 2021 - Am Soc Microbiol
Wolbachia is a maternally transmitted bacterium that manipulates arthropod and nematode
biology in myriad ways. The Wolbachia strain colonizing Drosophila melanogaster creates …

[HTML][HTML] Fitness of wAlbB Wolbachia infection in Aedes aegypti: parameter estimates in an outcrossed background and potential for population invasion

JK Axford, PA Ross, HL Yeap… - The American journal …, 2016 - ncbi.nlm.nih.gov
Wolbachia endosymbionts are potentially useful tools for suppressing disease transmission
by Aedes aegypti mosquitoes because Wolbachia can interfere with the transmission of …

[HTML][HTML] Systematic Review of Wolbachia Symbiont Detection in Mosquitoes: An Entangled Topic about Methodological Power and True Symbiosis

LM Inacio da Silva, FZ Dezordi, MHS Paiva, GL Wallau - Pathogens, 2021 - mdpi.com
Wolbachia is an endosymbiotic bacterium that naturally infects several arthropods and
nematode species. Wolbachia gained particular attention due to its impact on their host …

Impact of population age structure on Wolbachia transgene driver efficacy: ecologically complex factors and release of genetically modified mosquitoes

JL Rasgon, TW Scott - Insect biochemistry and molecular biology, 2004 - Elsevier
Wolbachia symbionts hold theoretical promise as a way to drive transgenes into insect
vector populations for disease prevention. For simplicity, current models of Wolbachia …

[HTML][HTML] Symbionts Commonly Provide Broad Spectrum Resistance to Viruses in Insects: A Comparative Analysis of Wolbachia Strains

J Martinez, B Longdon, S Bauer, YS Chan… - PLoS …, 2014 - journals.plos.org
In the last decade, bacterial symbionts have been shown to play an important role in
protecting hosts against pathogens. Wolbachia, a widespread symbiont in arthropods, can …

[HTML][HTML] Wolbachia Inhibits Binding of Dengue and Zika Viruses to Mosquito Cells

P Lu, Q Sun, P Fu, K Li, X Liang, Z Xi - Frontiers in microbiology, 2020 - frontiersin.org
As traditional approaches to the control of dengue and Zika are insufficient, significant efforts
have been made to develop utilization of the endosymbiotic bacterium Wolbachia to reduce …

Wolbachia strain wAlbB enhances infection by the rodent malaria parasite Plasmodium berghei in Anopheles gambiae mosquitoes

GL Hughes, J Vega-Rodriguez, P Xue… - Applied and …, 2012 - Am Soc Microbiol
Wolbachia, a common bacterial endosymbiont of insects, has been shown to protect its
hosts against a wide range of pathogens. However, not all strains exert a protective effect on …

Using Wolbachia to Eliminate Dengue: Will the Virus Fight Back?

KM Edenborough, HA Flores, CP Simmons… - Journal of …, 2021 - Am Soc Microbiol
Recent field trials have demonstrated that dengue incidence can be substantially reduced
by introgressing strains of the endosymbiotic bacterium Wolbachia into Aedes aegypti …

Successful establishment of Wolbachia in Aedes populations to suppress dengue transmission

AA Hoffmann, BL Montgomery, J Popovici… - Nature, 2011 - nature.com
Genetic manipulations of insect populations for pest control have been advocated for some
time, but there are few cases where manipulated individuals have been released in the field …