[HTML][HTML] Analysis of Antigens of Mycobacterium leprae by Interaction to Sera IgG, IgM, and IgA Response to Improve Diagnosis of Leprosy

A Kumar, O Parkash, BK Girdhar - BioMed research international, 2014 - hindawi.com
Till 2010, several countries have declared less than one leprosy patient among population
of 10,000 and themselves feeling as eliminated from leprosy cases. However, new leprosy …

[HTML][HTML] Diagnostic accuracy of tests using recombinant protein antigens of Mycobacterium leprae for leprosy: A systematic review

ALG de Oliveira, VG Fraga… - Journal of infection and …, 2020 - Elsevier
The aim of this systematic review was to investigate the studies that evaluated the sensitivity
and specificity of serologic tests using recombinant protein antigens from Mycobacterium …

Correspondence: A study on the methods for early serological diagnosis of leprosy and their potential use

Q Wu, X Li, Y Yin, H Shu - International Journal of Leprosy …, 1999 - search.proquest.com
This is a serial study. In this series we have established 12 methods for the early serological
diagnosis of leprosy, including the FLA-ABS test, ELISAs with artificial products (ND-O-, ND …

Serological detection of leprosy employing Mycobacterium leprae derived serine-rich 45 kDa, ESAT-6, CFP-10 and PGL-I: a compilation of data from studies in Indian …

O Parkash - Leprosy review, 2011 - leprosyreview.org
This article is a compilation of our findings recorded in the recent past where we have
investigated the serological performance of Mycobacterium leprae antigens like-serine-rich …

A recombinant chimeric antigen constructed with B-cell epitopes from Mycobacterium leprae hypothetical proteins is effective for the diagnosis of leprosy

BPN Assis, AT Chaves, DP Lage, MM Cardoso… - … and Infectious Disease, 2024 - Elsevier
The diagnosis if leprosy is difficult, as it requires clinical expertise and sensitive laboratory
tests. In this study, we develop a serological test for leprosy by using bioinformatics tools to …

Challenges in immunodiagnostic tests for leprosy

A Geluk - Expert opinion on medical diagnostics, 2013 - Taylor & Francis
Introduction: Despite the effectiveness of multidrug therapy, leprosy still represents a
significant global health problem: transmission of Mycobacterium leprae (M. leprae) is not …

Selection of antigens and development of prototype tests for point-of-care leprosy diagnosis

MS Duthie, GC Ireton, GV Kanaujia… - Clinical and vaccine …, 2008 - Am Soc Microbiol
Leprosy can be a devastating chronic infection that causes nerve function impairment and
associated disfigurement. Despite the recent reduction in the number of registered …

[HTML][HTML] Towards an immunodiagnostic test for leprosy

R Aráoz, N Honoré, S Banu, C Demangel… - Microbes and …, 2006 - Elsevier
In addition to multidrug therapy, elimination of leprosy requires improved diagnostic
methods. Using a comparative genomics approach, 17 potential protein antigens (MLP) that …

Recent advances in immunodiagnosis of leprosy.

B Sekar - Indian journal of leprosy, 2007 - europepmc.org
Although prevalence of leprosy is considerably reduced, the unabated emergence of about
300,000 cases worldwide indicates that the source of infection and transmission are not …

Comparative assessment of the leprosy antibody absorption test, Mycobacterium leprae extract enzyme-linked immunosorbent assay, and gelatin particle …

A Escobar-Gutiérrez, ME Amezcua… - Journal of clinical …, 1993 - Am Soc Microbiol
A comparative assessment of three serological methods for leprosy diagnosis (the
fluorescent leprosy antibody absorption [FLA-ABS] test, the Mycobacterium leprae soluble …