Since the discovery of the progesterone receptor antagonist mifepristone, numerous
additional compounds, which display a spectrum of biological actions ranging from full …

Since the discovery of the antiprogestin mifepristone, hundreds of similar compounds have
been synthesized, which can be grouped in a large family of progesterone receptor ligands …

Since the discovery of the antiprogestin RU 486 (mifepristone), other compounds have been
synthesised that function as pure progesterone antagonists or progesterone receptor …

Background: Synthetic compounds can bind to progesterone receptors and these
progesterone receptor ligands exhibit a spectrum of activities ranging from pure antagonism …

Since the original description of the structure of the antiprogestin, mifepristone, was
published, numerous related compounds have been synthesized which may function as …

Both progesterone receptor modulators (PRMs) as well as pure progesterone antagonists
(PAs) have numerous proven and potential therapeutic applications in female health care …

Since the description of the structure of the first progesterone receptor antagonist,
mifepristone, was published, numerous related compounds have been synthesized, which …

Many processes in female reproductive physiology depend on progesterone. This hormone
facilitates the action of estradiol in inducing the luteinizing hormone (LH) surge in the …

Selective progesterone receptor modulators (SPRMs) are a new class of compounds
developed to target the progesterone receptor (PR) with a mix of agonist and antagonist …

Background: A large number of synthetic compounds known as selective progesterone
receptor modulators can bind to progesterone receptors: the ligands exhibit a spectrum of …