Emerging data suggest that cancer stem cells (CSCs) exist in equilibrium with differentiated
cells and that stochastic transitions between these states can account for tumor …

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer
worldwide. Despite advances in diagnostic and therapeutic methods, survival of HNSCC …

Cancer stem cells (CSCs) are a subpopulation of tumor cells endowed with self-renewal
properties and the capacity to dynamically adapt to physiological changes that occur in the …

Cancer stem cells (CSCs) are a unique population of cells found within tumors that are able
to self-renew, restore the original heterogeneity of a tumor following treatment, and show …

The discovery of a small subset of cancer cells with self-renewal properties that can give rise
to phenotypically diverse tumour populations has shifted our understanding of cancer …

Head and Neck cancer survival has continued to remain around 50% despite treatment
advances. It is thought that cancer stem cells play a key role in promoting tumor …

Head and neck squamous cell carcinoma (HNSCC) represents frequent yet aggressive
tumours that encompass complex ecosystems of stromal and neoplastic components …

Human head and neck cancer (HNC) is a highly heterogeneous disease. Understanding the
biology of HNC progression is necessary for the development of novel approaches to its …

ABSTRACT Background Cancer stem cells (CSCs) represent a subpopulation of cells
responsible for tumor growth. Their role in head and neck squamous cell carcinoma …

Accumulating evidence suggests that self-renewal and differentiation capabilities reside
only in a subpopulation of tumor cells, termed cancer stem cells (CSCs), whereas the …