[HTML][HTML] MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets

A Kurioka, JE Ussher, C Cosgrove, C Clough… - Mucosal …, 2015 - Elsevier
Mucosal-associated invariant T (MAIT) cells are an innate-like T-cell population restricted by
the non-polymorphic, major histocompatibility complex class I-related protein 1, MR1. MAIT …

[HTML][HTML] Arming of MAIT cell cytolytic antimicrobial activity is induced by IL-7 and defective in HIV-1 infection

E Leeansyah, J Svärd, J Dias, M Buggert… - PLoS …, 2015 - journals.plos.org
Mucosa-associated invariant T (MAIT) cells represent a large innate-like evolutionarily
conserved antimicrobial T-cell subset in humans. MAIT cells recognize microbial riboflavin …

Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota

A Cebula, M Seweryn, GA Rempala, SS Pabla… - Nature, 2013 - nature.com
Peripheral mechanisms preventing autoimmunity and maintaining tolerance to commensal
microbiota involve CD4+ Foxp3+ regulatory T (Treg) cells, generated in the thymus or …

[HTML][HTML] Novel antigen-presenting cell imparts Treg-dependent tolerance to gut microbiota

B Akagbosu, Z Tayyebi, G Shibu, YA Paucar Iza… - Nature, 2022 - nature.com
Establishing and maintaining tolerance to self-antigens or innocuous foreign antigens is vital
for the preservation of organismal health. Within the thymus, medullary thymic epithelial cells …

[HTML][HTML] B cells modulate mucosal associated invariant T cell immune responses

R Salerno-Goncalves, T Rezwan… - Frontiers in …, 2014 - frontiersin.org
A common finding when measuring T cell immunity to enteric bacterial vaccines in humans
is the presence of background responses among individuals before immunization. Yet the …

[HTML][HTML] MAIT cells, guardians of skin and mucosa?

I Nel, L Bertrand, A Toubal, A Lehuen - Mucosal immunology, 2021 - Elsevier
Abstract Mucosal Associated Invariant T (MAIT) cells are evolutionary conserved innate-like
T cells able to recognize bacterial and fungal ligands derived from vitamin B biosynthesis …

MAIT cells are critical for optimal mucosal immune responses during in vivo pulmonary bacterial infection

A Meierovics, WJC Yankelevich… - Proceedings of the …, 2013 - National Acad Sciences
Mucosa-associated invariant T (MAIT) cells are “innate” T cells that express an invariant T-
cell receptor α-chain restricted by the nonclassical MHC class I molecule MHC-related …

Mucosal-associated invariant T cells and disease

A Toubal, I Nel, S Lotersztajn, A Lehuen - Nature Reviews Immunology, 2019 - nature.com
Mucosal-associated invariant T (MAIT) cells are unique innate-like T cells that bridge innate
and adaptive immunity. They are activated by conserved bacterial ligands derived from …

[HTML][HTML] Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals

Z Chen, H Wang, C D'souza, S Sun, L Kostenko… - Mucosal …, 2017 - nature.com
Despite recent breakthroughs in identifying mucosal-associated invariant T (MAIT) cell
antigens (Ags), the precise requirements for in vivo MAIT cell responses to infection remain …

MAIT cells and microbial immunity

EW Meermeier, MJ Harriff, E Karamooz… - Immunology and cell …, 2018 - Wiley Online Library
Mucosal‐associated invariant T (MAIT) cells, the most abundant T‐cell subset in humans,
are increasingly being recognized for their importance in microbial immunity. MAIT cells …