Polyvinylpyrrolidone-coated gold nanoparticles inhibit endothelial cell viability, proliferation, and ERK1/2 phosphorylation and reduce the magnitude of endothelial …
T Mohamed, S Matou-Nasri, A Farooq… - International journal …, 2017 - Taylor & Francis
Background Gold nanoparticles (AuNPs) demonstrate clinical potential for drug delivery and
imaging diagnostics. As AuNPs aggregate in physiological fluids, polymer-surface …
imaging diagnostics. As AuNPs aggregate in physiological fluids, polymer-surface …
[HTML][HTML] Synthesis of functionalized 10-nm polymer-coated gold particles for endothelium targeting and drug delivery
MJ Cheng, P Prabakaran, R Kumar… - Journal of …, 2018 - pmc.ncbi.nlm.nih.gov
Gold nanoparticles (AuNPs) have been used extensively in medical research due to their
size, biocompatibility, and modifiable surface. Specific targeting and drug delivery are some …
size, biocompatibility, and modifiable surface. Specific targeting and drug delivery are some …
Gold nanoparticle interactions with endothelial cells cultured under physiological conditions
C Freese, L Anspach, RC Deller, SJ Richards… - Biomaterials …, 2017 - pubs.rsc.org
PEGylated gold nanoparticles (AuNPs) have an extended circulation time after intravenous
injection in vivo and exhibit favorable properties for biosensing, diagnostic imaging, and …
injection in vivo and exhibit favorable properties for biosensing, diagnostic imaging, and …
Uptake of gold nanoparticles in primary human endothelial cells
Gold nanoparticles (AuNPs) are relevant in nanomedicine for drug delivery in the vascular
system, where endothelial cells are the first point of contact. We investigated the uptake of …
system, where endothelial cells are the first point of contact. We investigated the uptake of …
Gold nanoparticles compromise TNF-α-induced endothelial cell adhesion molecule expression through NF-κB and protein degradation pathways and reduce …
The aim of this study was to investigate the anti-inflammatory effects and mechanism of
action of the gold nanoparticles (AuNPs) on vascular injury. In vitro vascular endothelial cell …
action of the gold nanoparticles (AuNPs) on vascular injury. In vitro vascular endothelial cell …
Gold nanoparticles disrupt actin organization and pulmonary endothelial barriers
This study explored the impact of gold nanoparticles on the metabolic activity and
morphology of human pulmonary endothelial cell monolayers. We developed a gold …
morphology of human pulmonary endothelial cell monolayers. We developed a gold …
Nanoparticle size-specific actin rearrangement and barrier dysfunction of endothelial cells
Y Liu, N Rogel, K Harada, L Jarett, CH Maiorana… - …, 2017 - Taylor & Francis
In this work, we evaluated the impact of gold nanoparticles on endothelial cell behavior and
function beyond the influence on cell viability. Five types of gold nanoparticles were studied …
function beyond the influence on cell viability. Five types of gold nanoparticles were studied …
Evaluation of gold nanoparticles biocompatibility: a multiparametric study on cultured endothelial cells and macrophages
A Orlando, M Colombo, D Prosperi, F Corsi… - Journal of Nanoparticle …, 2016 - Springer
Colloidal gold nanoparticles (AuNPs) have been considered an established advanced tool
in biomedicine thanks to their physicochemical properties combined with nanoscale size …
in biomedicine thanks to their physicochemical properties combined with nanoscale size …
Low-dose albumin-coated gold nanorods induce intercellular gaps on vascular endothelium by causing the contraction of cytoskeletal actin
Z Li, J Liu, K Ballard, C Liang, C Wang - Journal of Colloid and Interface …, 2023 - Elsevier
Cytotoxicity of nanoparticles, typically evaluated by biochemical-based assays, often
overlook the cellular biophysical properties such as cell morphology and cytoskeletal actin …
overlook the cellular biophysical properties such as cell morphology and cytoskeletal actin …
Gold nanoparticles increase endothelial paracellular permeability by altering components of endothelial tight junctions, and increase blood-brain barrier permeability …
CH Li, MK Shyu, C Jhan, YW Cheng… - Toxicological …, 2015 - academic.oup.com
Abstract Gold nanoparticles (Au-NPs) are being increasingly used as constituents in
cosmetics, biosensors, bioimaging, photothermal therapy, and targeted drug delivery. This …
cosmetics, biosensors, bioimaging, photothermal therapy, and targeted drug delivery. This …
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