Safety and immunogenicity of a combined Tetanus, Diphtheria, recombinant acellular Pertussis vaccine (TdaP) in healthy Thai adults

C Sirivichayakul, P Chanthavanich… - Human vaccines & …, 2017 - Taylor & Francis
ABSTRACT Background: An acellular Pertussis (aP) vaccine containing recombinant
genetically detoxified Pertussis Toxin (PTgen), Filamentous Hemagglutinin (FHA) and …

A phase I, randomized, controlled, dose-ranging study of investigational acellular pertussis (aP) and reduced tetanus-diphtheria-acellular pertussis (TdaP) booster …

G Leroux-Roels, M Lattanzi, CD Solis… - Human Vaccines & …, 2018 - Taylor & Francis
Despite high vaccination coverage worldwide, pertussis has re-emerged in many countries.
This randomized, controlled, observer-blind phase I study and extension study in Belgium …

A randomised, double-blind, non-inferiority clinical trial on the safety and immunogenicity of a tetanus, diphtheria and monocomponent acellular pertussis (TdaP) …

B Thierry-Carstensen, K Jordan, HH Uhlving, T Dalby… - Vaccine, 2012 - Elsevier
BACKGROUND: Increasing incidence of pertussis in adolescents and adults has stimulated
the development of safe and immunogenic acellular pertussis vaccines for booster …

A randomised controlled trial with a diphtheria–tetanus–acellular pertussis (dTpa) vaccine in adults

M Van der Wielen, P Van Damme, E Joossens… - Vaccine, 2000 - Elsevier
The aim of this assessor-blinded trial was to compare the immunogenicity and reactogenicity
of a candidate diphtheria, tetanus toxoids and acellular pertussis vaccine with reduced …

Immunogenicity and reactogenicity of a single dose of a diphtheria–tetanus–acellular pertussis component vaccine (DTaP) compared to a diphtheria–tetanus toxoid …

I Bartels, J Jüngert, S Lugauer, K Stehr, U Heininger - Vaccine, 2001 - Elsevier
We compared immunogenicity and reactogenicity of a single dose of DTaP vaccine
(containing tetanus and diphtheria toxoids and four acellular pertussis antigens) with …

[PDF][PDF] Immunogenicity and reactogenicity of a reduced-antigen-content diphtheria-tetanus-acellular pertussis vaccine as a single-dose booster in Singaporean adults

SH Chan, PTN Tan, HH Han, HL Bock - Singapore medical journal, 2006 - smj.org.sg
Introduction: Older children and adults, susceptible to pertussis because of waning
immunity, may serve as a reservoir of infection, leading to severe disease among young …

Immunogenicity of a combined diphtheria–tetanus–acellular pertussis vaccine in adults

P Van Damme, M Burgess - Vaccine, 2004 - Elsevier
Two clinical studies were undertaken to evaluate the immunogenicity of an adult-type dTpa
booster vaccine (Boostrix™ by GlaxoSmithKline Biologicals). Blood samples taken prior to …

Overview of the clinical development of a diphtheria-tetanus-acellular pertussis vaccine

H Bogaerts, C Capiau, P Hauser… - Journal of Infectious …, 1996 - academic.oup.com
A tricomponent acellular pertussis vaccine containing pertussis toxoid, filamentous
hemagglutinin, and pertactin combined with diphtheria and tetanus toxoids (DTPa) was …

Development and clinical testing of multivalent vaccines based on a diphtheria–tetanus–acellular pertussis vaccine: difficulties encountered and lessons learned

C Capiau, J Poolman, B Hoet, H Bogaerts, F Andre - Vaccine, 2003 - Elsevier
The widespread use of whole-cell pertussis vaccines in the second half of the 20th century
have reduced the incidence of the disease significantly. However, in some countries …

Safety and immunogenicity of an indigenously developed tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine (Tdap) in adults, adolescents, and children …

HJ Sharma, S Parekh, P Pujari, S Shewale… - Expert Review of …, 2023 - Taylor & Francis
Background This study assessed safety and immunogenicity of Serum Institute of India Pvt
Ltd (SIIPL)'s tetanus toxoid (TT), diphtheria toxoid (DT), and acellular pertussis booster …