OBJECTIVES: To assess the safety and tolerability of 12 lots of SmithKline Beecham
Biologicals' diphtheria-tetanus-tricomponent acellular pertussis vaccine (DTaP) in a large …

Combination vaccines containing a monocomponent acellular pertussis (aP) vaccine,
manufactured at Statens Serum Institut (SSI), Denmark, have successfully controlled …

Three hundred and nineteen adolescents aged 10–12 years who had been previously
vaccinated with five doses of acellular pertussis-containing vaccines received single doses …

BACKGROUND: Although decennial adult boosters of tetanus and diphtheria toxoids are
recommended in Canada and the United States, a second dose of pertussis vaccine is not …

Combined pediatric vaccines have the advantages of conferring protection against multiple
common infectious diseases with a reduced number of injections. Their use should lead to …

The introduction of acellular pertussis (Pa) vaccines in countries with a low uptake of whole-
cell pertussis (Pw) vaccines has led to a dramatic reduction in pertussis disease. Diphtheria …

Background: Adult formulation tetanus and diphtheria toxoids and acellular pertussis
vaccines (Tdap) have been developed to prevent pertussis in adolescents and adults. There …

Background. Booster vaccination against tetanus and diphtheria at 10-year intervals is
commonly recommended. Reduced antigen content diphtheria and tetanus toxoids and …

Objective. This case-control study investigated the protective efficacy against pertussis of
three doses of a two-component acellular pertussis vaccine (manufactured by Biken in …

The recent increase of pertussis in young adults in Japan is hypothesized to be due in part
to waning protection from the acellular pertussis vaccine. While a booster immunization may …