Although nitric oxide (. N= O) biosynthesis is inducible in rat hepatocytes (HC), the
physiological significance of. N= O production by these cells is unknown. Short exposure of …

To elucidate the role of nitric oxide (NO) in the regulation of mitochondrial function, the effect
of NO on energy transfer reactions was examined under different oxygen tensions …

• Nitric oxide, a highly reactive radical, was recently identified as an intermediate of L-
arginine metabolism in mammalian cells. We have shown that nitric oxide synthesis is …

The effects of endogenous production of NO•, catalysed by the mitochondrial nitric oxide
synthase (NOS), on mitochondrial metabolism were studied. The respiratory rates of intact …

Nitric oxide (NO) and its derivatives inhibit mitochondrial respiration by various means. The
author and others have shown that low (nanomolar) concentrations of NO immediately …

Nitric oxide (NO) and its derivatives inhibit mitochondrial respiration by a variety of means.
Nanomolar concentrations of NO immediately, specifically and reversibly inhibit cytochrome …

Nitric oxide (· NO) released byS-nitrosoglutathione (GSNO) inhibited enzymatic activities of
rat heart mitochondrial membranes. Cytochrome oxidase activity was inhibited to one-half at …

Nitric oxide (NO) and its derivative peroxynitrite (ONOO−) inhibit mitochondrial respiration by
distinct mechanisms. Low (nanomolar) concentrations of NO specifically inhibit cytochrome …

Nitric oxide (NO) inhibited the respiration rate of mitochondria isolated from rat heart at sub-
micromolar concentrations of NO. The inhibition was rapidly and completely reversible …

Nitric oxide (NO) reversibly inhibits mitochondrial respiration by competing with oxygen at
cytochrome oxidase. Concentrations of NO measured in a range of biological systems are …