Effect of adiponectin and ghrelin on apoptosis of Barrett adenocarcinoma cell line

PC Konturek, G Burnat, T Rau, EG Hahn… - Digestive diseases and …, 2008 - Springer
Background Obesity is an important risk factor for Barrett adenocarcinoma. However, the
role of adiponectin (anti-inflammatory adipokine from adipose tissue) and ghrelin …

Age‐specific risk factor profiles of adenocarcinomas of the esophagus: A pooled analysis from the international BEACON consortium

J Drahos, Q Xiao, HA Risch… - … journal of cancer, 2016 - Wiley Online Library
Esophageal (EA) and esophagogastric junction (EGJA) adenocarcinoma have been steadily
increasing in frequency in younger people; however, the etiology of these cancers is poorly …

Development and validation of a model to determine risk of progression of Barrett's esophagus to neoplasia

S Parasa, S Vennalaganti, S Gaddam, P Vennalaganti… - Gastroenterology, 2018 - Elsevier
Background & Aims A system is needed to determine the risk of patients with Barrett's
esophagus for progression to high-grade dysplasia (HGD) and esophageal …

Circulating leptin and inflammatory response in esophageal cancer, esophageal cancer-related cachexia–anorexia syndrome (CAS) and non-malignant CAS of the …

D Diakowska, M Krzystek-Korpacka… - Cytokine, 2010 - Elsevier
We investigated the association between esophageal cancer and cachexia–anorexia
syndrome (CAS) of the alimentary tract and leptin, an adipocytokine crucial for body weight …

Risk factors for progression of Barrett's esophagus to high grade dysplasia and esophageal adenocarcinoma

S Kambhampati, AH Tieu, B Luber, H Wang… - Scientific reports, 2020 - nature.com
Barrett's esophagus (BE) is the only known precursor to esophageal adenocarcinoma
(EAC). Methods of identifying BE patients at high risk for progression to high-grade …

Medications (NSAIDs, statins, proton pump inhibitors) and the risk of esophageal adenocarcinoma in patients with Barrett's esophagus

DM Nguyen, P Richardson, HB El–Serag - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Limited evidence suggests that proton pump inhibitors (PPI),
nonsteroidal anti-inflammatory drugs (NSAID)/aspirin, and statins may be associated with a …

Current and past smoking significantly increase risk for Barrett's esophagus

KJ Smith, SM O'Brien, AC Green, PM Webb… - Clinical …, 2009 - Elsevier
BACKGROUND & AIMS: Barrett's esophagus (BE) is the precursor to esophageal
adenocarcinoma; the incidence of this cancer is rapidly increasing in Western populations …

Risk of mortality and cancer incidence in Barrett's esophagus

MB Cook, CP Wild, SM Everett, LJ Hardie… - … Biomarkers & Prevention, 2007 - AACR
Background: There are very few prospective follow-up studies of Barrett esophagus (BE)
cohorts assessing the risk of extraesophageal cancer incidence or mortality. Such studies …

Body weight trajectories and risk of oesophageal and gastric cardia adenocarcinomas: a pooled analysis of NIH-AARP and PLCO Studies

JL Petrick, SP Kelly, LM Liao, ND Freedman… - British journal of …, 2017 - nature.com
Background: Elevated body mass index (BMI, kg m− 2) has been consistently associated
with oesophageal adenocarcinoma (EA) and gastric cardia adenocarcinoma (GCA) …

Leptin and gastro‐intestinal malignancies

JM Howard, GP Pidgeon, JV Reynolds - Obesity Reviews, 2010 - Wiley Online Library
Obesity is a well‐established risk factor for the development and mortality from several
cancers, including adenocarcinoma of the oesophagus, oesophago‐gastric junction and …