Diabetes mellitus is characterized by chronic hyperglycemia with disturbances of
carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin …

Diabetes mellitus (DM) is a progressive disease characterized by insulin deficiency and
insulin resistance or both. The fasting and post-prandial blood glucose is elevated, exposing …

The first therapeutic use of insulin by Frederick Banting and Charles Best in 1921
revolutionized the management of type 1 diabetes and considerably changed the lives of …

The discovery of insulin over 100 years ago provided a muchneeded lifeline for patients with
diabetes. Since that time patients with type 1 diabetes (T1DM) have seen progress in the …

Diabetes mellitus is a chronic progressive disease that has profound consequences for
individuals, families, and society. Despite clear glycemic control targets articulated by the …

A multitude of new treatment options for individuals living with type 1 diabetes mellitus
(T1DM) are currently in development or have recently been approved. Recognizing the …

This thesis on old and new approaches to treatment diabetes mellitus type 1 aims at giving
an insight at various aspects of this chronic disease management. Type 1 diabetes mellitus …

It will not be long before we are celebrating the centenary of the clinical use of insulin.
Indeed, it is already more than 100 years since Sir Edward Albert Sharpey-Schafer (in 1910) …

Type 2 diabetes mellitus is a chronic metabolic disorder that results from defects in both
insulin secretion and insulin action. Type 2 diabetes can initially be treated with oral agent …

OBJECTIVE: This review is intended to explore the pathophysiology of type 2 diabetes,
examine the role of insulin as a means of achieving glycemic control in people with type 2 …