The preeminent treatments for neurodegenerative disease are often unavailable due to the
poor accessibility of therapeutic drugs. Moreover, the blood–brain barrier (BBB) effectively …

Parkinson's disease (PD) arises as neurodegenerative disorder and characterized by
progressive deterioration of motor functions due to forfeiture of dopamine-releasing neurons …

Neuro-inflammation is a pivotal physio-pathological feature of brain disorders, including
neurodegenerative diseases. As such, it is a relevant therapeutic target against which drugs …

Aim: Our goal was to develop an efficient nanoparticle-based system that can overcome the
restrictive mechanism of the blood–brain barrier (BBB) by targeting insulin receptors and …

The elaboration of nanotechnology offers valuable therapeutic options to overcome the
blood-brain barrier and enable the treatment of brain diseases. However, to date, limit work …

The blood–brain barrier (BBB) plays an irreplaceable role in protecting the central nervous
system (CNS) from bloodborne pathogens. However, the BBB complicates the treatment of …

The blood–brain barrier (BBB), a unique structure in the central nervous system (CNS),
protects the brain from bloodborne pathogens by its excellent barrier properties …

The blood–brain barrier (BBB) is a protective endothelial barrier lining the brain
microvasculature which prevents brain delivery of therapies against brain diseases. Hence …

Current treatments for Parkinson's disease (PD) are aimed at addressing motor symptoms
but there is no therapy focused on modifying the course of the disease. Successful treatment …

Effective intervention is essential to combat the coming epidemic of neurodegenerative (ND)
diseases. Nanomedicine can overcome restrictions of CNS delivery imposed by the blood …