“Virtual”(computed) fractional flow reserve: current challenges and limitations

PD Morris, FN van de Vosse, PV Lawford… - JACC: Cardiovascular …, 2015 - jacc.org
Fractional flow reserve (FFR) is the “gold standard” for assessing the physiological
significance of coronary artery disease during invasive coronary angiography. FFR-guided …

Fractional flow reserve compared with intravascular ultrasound guidance for optimizing stent deployment

WF Fearon, J Luna, H Samady, ER Powers… - Circulation, 2001 - Am Heart Assoc
Background Determination of fractional flow reserve (FFR) has been proposed as a means
to assess stent deployment. In this prospective, multicenter trial, we evaluate the use of FFR …

Hybrid iFR-FFR decision-making strategy: implications for enhancing universal adoption of physiology-guided coronary revascularization

R Petraco, JJ Park, S Sen, S Nijjer, I Malik… - American Journal of …, 2013 - ajconline.org
Background Adoption of fractional flow reserve (FFR) remains low (6-8%), partly because of
the time, cost and potential inconvenience associated with vasodilator administration. The …

Coronary computed tomography angiography–derived fractional flow reserve: an expert consensus document of Chinese Society of Radiology

LJ Zhang, C Tang, P Xu, B Guo, F Zhou… - Journal of Thoracic …, 2022 - journals.lww.com
Invasive fractional flow reserve (FFR) measured by a pressure wire is a reference standard
for evaluating functional stenosis in coronary artery disease. Coronary computed …

Fractional flow reserve: a useful index to evaluate the influence of an epicardial coronary stenosis on myocardial blood flow

NHJ Pijls, B Van Gelder, P Van der Voort, K Peels… - Circulation, 1995 - Am Heart Assoc
Background Fractional flow reserve (FFR), defined as the ratio of maximum flow in the
presence of a stenosis to normal maximum flow, is a lesion-specific index of stenosis …

Accuracy and reproducibility of fast fractional flow reserve computation from invasive coronary angiography

AR Van Rosendael, G Koning… - … International Journal of …, 2017 - Springer
Fractional flow reserve (FFR) guided percutaneous coronary intervention (PCI) is associated
with favourable outcome compared with revascularization based on angiographic stenosis …

Accuracy of fractional flow reserve derived from coronary angiography

WF Fearon, S Achenbach, T Engstrom, A Assali… - Circulation, 2019 - Am Heart Assoc
Background: Measuring fractional flow reserve (FFR) with a pressure wire remains
underutilized because of the invasiveness of guide wire placement or the need for a …

CT-derived fractional flow reserve (CT-FFR) in the evaluation of coronary artery disease

N Khav, AR Ihdayhid, B Ko - Heart, Lung and Circulation, 2020 - Elsevier
Fractional flow reserve derived from coronary computed tomography enables anatomical
and haemodynamic assessment of coronary artery disease in a single non-invasive test. Its …

Novel indices of coronary physiology: do we need alternatives to fractional flow reserve?

GL De Maria, HM Garcia-Garcia… - Circulation …, 2020 - Am Heart Assoc
Fractional flow reserve is the current invasive gold standard for assessing the ischemic
potential of an angiographically intermediate coronary stenosis. Procedural cost and time …

Relationship between FFR, CFR and coronary microvascular resistance–Practical implications for FFR-guided percutaneous coronary intervention

D Garcia, B Harbaoui, TP van de Hoef, M Meuwissen… - PloS one, 2019 - journals.plos.org
Objective The aim was threefold: 1) expound the independent physiological parameters that
drive FFR, 2) elucidate contradictory conclusions between fractional flow reserve (FFR) and …