Purpose The main objective of static cold storage is to reduce cellular metabolic demands to
extend the period of ischaemia prior to transplantation. Hypothermia does not halt …

Background Deceased donor kidneys are preserved in cold hypoxic conditions. Providing
oxygen during preservation might improve post-transplant outcomes, particularly for kidneys …

We reviewed the evidence for ex-vivo Supplemental Oxygen during Hypothermic
preservation (SOH) for deceased donor kidneys. Bibliographic databases were searched for …

Introduction The current methods of preserving donor kidneys in nonoxygenated cold
conditions minimally protect the kidney against ischemia-reperfusion injury (IRI), a major …

Static cold storage (SCS) and hypothermic machine perfusion (HMP) are currently standard
methods for renal grafts clinical preservation. Both methods are predominantly implemented …

Background: The two main options for renal allograft preservation are static cold storage
(CS) and machine perfusion (MP). There has been considerably increased interest in MP …

Background Hypothermia, leading to mitochondrial inhibition, is widely used to reduce
ischemic injury during kidney preservation. However, the exact effect of hypothermic kidney …

Kidney transplantation has become a well-established treatment option for patients with end-
stage renal failure. The persisting organ shortage remains a serious problem. Therefore, the …

Introduction Cold storage of organs for preservation and transplantation is reaching its limits
especially with extended criteria for heart beating donors and donation after cardiac death …

Organ preservation has historically relied on the concept that by reducing the temperature to
4 C, cellular metabolism is reduced to approximately 10% of normal. 1 Therefore, it is …