Brugada Syndrome: cellular mechanisms and approaches to therapy

C Antzelevitch, S Viskin - Electrical Diseases of the Heart: Volume 1: Basic …, 2013 - Springer
Abstract The Brugada Syndrome, introduced as a new clinical entity 20 years ago, has
attracted great interest because of its prevalence and association with high risk of sudden …

Delayed depolarization and histologic abnormalities underlie the Brugada syndrome

B Martini, N Martini, L De Mattia… - Pacing and Clinical …, 2023 - Wiley Online Library
Brugada syndrome (BrS) is a controversial disease whose pathophysiology is still far from
being fully understood. Unlike other cardiological disorders, a definite etiology has not yet …

Brugada syndrome and reduced right ventricular outflow tract conduction reserve: a final common pathway?

ER Behr, Y Ben-Haim, MJ Ackerman… - European heart …, 2021 - academic.oup.com
Brugada syndrome (BrS) was first described as a primary electrical disorder predisposing to
the risk of sudden cardiac death and characterized by right precordial lead ST elevation …

The pathophysiological mechanism underlying Brugada syndrome: depolarization versus repolarization

AAM Wilde, PG Postema, JM Di Diego, S Viskin… - Journal of molecular and …, 2010 - Elsevier
The pathophysiological mechanism underlying Brugada syndrome: Depolarization versus
repolarization - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & …

Mechanisms of arrhythmias in the brugada syndrome

M Blok, BJ Boukens - International journal of molecular sciences, 2020 - mdpi.com
Arrhythmias in Brugada syndrome patients originate in the right ventricular outflow tract
(RVOT). Over the past few decades, the characterization of the unique anatomy and …

Brugada syndrome

B Benito, R Brugada, J Brugada, P Brugada - Progress in cardiovascular …, 2008 - Elsevier
Since its first description in 1992 as a new clinical entity, the Brugada syndrome has
aroused great interest among physicians and basic scientists. Two consensus conferences …

[HTML][HTML] Repolarization versus depolarization defects in Brugada syndrome: a tale of 2 different electrophysiologic settings?

K Nademanee, AAM Wilde - Clinical Electrophysiology, 2017 - jacc.org
The intense but animated debate between the repolarization versus depolarization
hypotheses as the underlying electrophysiologic mechanism of the Brugada syndrome (BrS) …

Arrhythmogenesis in Brugada syndrome: impact and constrains of current concepts

M Bébarová - International journal of cardiology, 2013 - Elsevier
Brugada syndrome (BrS), an inherited arrhythmogenic disease first described in 1992, is
characterized by ST segment elevations on the electrocardiogram in the right precordium …

Brugada syndrome: clinical, genetic, molecular, cellular and ionic aspects

C Antzelevitch - Expert review of cardiovascular therapy, 2003 - Taylor & Francis
Brugada syndrome, first described as a new clinical entity by Pedro and Josep Brugada in
1992, has attracted great interest because of its high prevalence in many regions of the …

Pathogenesis and management of Brugada syndrome

J Sieira, G Dendramis, P Brugada - Nature Reviews Cardiology, 2016 - nature.com
Brugada syndrome is an inherited disease characterized by an increased risk of sudden
cardiac death owing to ventricular arrhythmias in the absence of structural heart disease …