A novel noninvasive magnetic resonance imaging (MRI) method was developed to
determine in vivo blood oxygen saturation and its changes during motor cortex activation in …

Since Ogawa et al.(Proc Natl Acad Sci USA 1990; 87: 9868–9872) made the fundamental
discovery of blood oxygenation leveldependent (BOLD) contrast in MRI, most efforts have …

This research investigates the hemodynamic response to stimulation of the barrel cortex in
anaesthetized rats using optical imaging and spectroscopy (Bonhoeffer and Grinvald, 1996; …

The linearity of the cerebral perfusion response relative to stimulus duration is an important
consideration in the characterization of the relationship between regional cerebral blood …

Changes in cerebral blood flow (CBF), volume (CBV), and oxygenation (blood-oxygenation
level dependent (BOLD)) during functional activation are important for calculating changes …

Dynamic FLASH (fast low‐angle shot) magnetic resonance (MR) imaging was used to
monitor changes in brain oxygenation in the human visual cortex during photic stimulation …

The sensitivity of MRI for local changes in the deoxyhemoglobin concentration is the basis of
the blood oxygen level dependent (BOLD) effect. Time-resolved fMRI studies during visual …

The brain's response to functional activation is characterized by focal increases in cerebral
blood flow. It is generally assumed that this hyperemia is a direct response to the energy …

Stimulus‐related signal changes in functional MRI of human brain activation not only reflect
associated adjustments of cerebral blood flow and oxygen consumption, but strongly …

It recently has been demonstrated that magnetic resonance imaging can be used to map
changes in brain hemodynamics produced by human mental operations. One method under …